ArticleCancer epidemiology2024
Lung cancer mortality trends and disparities: A cross-sectional analysis 1999-2020.
Article in Cancer epidemiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- A 25 year nationwide analysis of mortality trends from cerebrovascular diseases in patients with lung cancer (1999-2023).Annals of medicine and surgery (2012) · 2026Article
- Trends in cardiovascular mortality among lung cancer patients in the United States: a retrospective study from 1999 to 2023.Cardio-oncology (London, England) · 2026Article
- Bronchus and lung cancer-related mortality trends in the United States from 1999 to 2023.Journal of cardiothoracic surgery · 2026Article
- Prediction of pulmonary infection during chemotherapy in non-small cell lung cancer: development and internal validation of a nomogram.Frontiers in oncology · 2026Article
- Lung cancer clusters and air pollution exposure in Wayne County, Michigan: an autoregressive distributed lag model.Journal of thoracic disease · 2025Article
- Racial disparities in the cause of death among patients with lung cancer in the United States.Journal of thoracic disease · 2025Article
- A study on the application and effect of ERAS-based refined nursing in patients undergoing radical lung cancer surgery.Frontiers in surgery · 2025Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundLung cancer remains a leading cause of morbidity and mortality in the United States. Given the importance of epidemiological insight on lung cancer outcomes as the foundation for targeted interventions, we aimed to examine lung cancer death trends in the United States in the recent 22-year period, exploring demographic disparities and yearly mortality shifts.
methodsMortality information was obtained from the CDC Wide-ranging Online Data for Epidemiologic Research database from the years 1999-2020. Demographic information included age, sex, race or ethnicity, and area of residence. We performed log-linear regression models to assess temporal mortality shifts and calculated average annual percentage change (AAPC) and compared age-adjusted mortality rates (AAMR) across demographic subpopulations.
resultsA total of 3,380,830 lung cancer deaths were identified. The AAMR decreased from 55.4 in 1999-31.8 in 2020 (p<0.001). Males (AAMR 57.6) and non-Hispanic (NH) (AAMR 47.5) populations were disproportionately impacted compared to females (AAMR 36.0) and Hispanic (AAMR 19.1) populations, respectively. NH Black populations had the highest AAMR (48.5) despite an overall reduction in lung cancer deaths (AAPC -3.3 %) over the study period. Although non-metropolitan regions were affected by higher mortality rates, the annual decrease in mortality among metropolitan regions (AAPC -2.8 %, p<0.001) was greater compared to non-metropolitan regions (AAPC -1.7 %, p<0.001). Individuals living in the Western US (AAPC -3.4 %, p<0.001) experienced the greatest decline in lung cancer mortality compared to other US census regions.
conclusionsOur findings revealed lung cancer mortality inequalities in the US. By contextualizing these mortality shifts, we provide a larger framework of data-driven initiatives for societal and health policy changes for improving access to care, minimizing healthcare inequalities, and improving outcomes.
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