Evidence map›Paper›PMID 39196931›Full record

ArticleScience advances2024

PneumaOCT: Pneumatic optical coherence tomography endoscopy for targeted distortion-free imaging in tortuous and narrow internal lumens.

Tinghua Zhang, Sishen Yuan, Chao Xu, Peng Liu, Hing-Chiu Chang, Sze Hang Calvin Ng, Hongliang Ren, Wu Yuan

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Soft Artificial Ciliary Brush with Integrated Haptic Feedback for Efficient Airway Mucus Cleaning.Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tinghua ZhangDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0001-8559-4458
Sishen YuanDepartment of Electronic Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0001-5095-5372
Chao XuDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0001-8096-7489
Peng LiuDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0001-6363-5589
Hing-Chiu ChangDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0001-8634-328X
Sze Hang Calvin NgDepartment of Surgery, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-8074-0900
Hongliang RenDepartment of Electronic Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-6488-1551
Wu YuanDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0001-9405-519X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complex anatomy of internal luminal organs, like bronchioles, poses challenges for endoscopic optical coherence tomography (OCT). These challenges include limited steerability for targeted imaging and nonuniform rotation distortion (NURD) with proximal scanning. Using rotary micromotors for distal scanning could address NURD but raises concerns about electrical safety and costs. We present pneumaOCT, the first pneumatic OCT endoscope, comprising a steerable catheter with a soft pneumatic actuator and an imaging probe with a miniature pneumatic turbine. With a diameter of 2.8 mm, pneumaOCT allows for a bending angle of up to 237°, facilitating navigation through narrow turns. The pneumatic turbine enables adjustable imaging speeds from 51 to 446 revolutions per second. We demonstrate the pneumaOCT in vivo imaging of mouse esophagus and colon, as well as targeted and distortion-free imaging of peripheral bronchioles in a bronchial phantom and a porcine lung. This advancement substantially improves endoscopic OCT for navigational imaging in curved and narrow lumens.

Indexed as

Tomography, Optical CoherenceAnimalsBronchiolesColonEndoscopyEsophagusMicePhantoms, ImagingSwine

Identifiers

PMID39196931
PMCPMC11352845

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.