Evidence map›Paper›PMID 39196491›Full record

ArticleJournal of racial and ethnic health disparities2025

Associations Between Opioid and Kratom Use in the USA: Differences by Race/Ethnicity and Sexual Orientation.

Cassidy R LoParco, Carlton Bone, Carla J Berg, Matthew E Rossheim, Noah C Peeri, Kayla K Tillett, Dong-Chul Seo

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of racial and ethnic health disparities, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Profiles of quality of life among US young adult cancer survivors and their associations with potential psychosocial intervention targets of hope and psychological flexibility.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cassidy R LoParcoMilken Institute School of Public Health, George Washington University, Washington, DC, USA. cassidy.loparco@email.gwu.edu.ORCID 0000-0003-4206-4179
Carlton BoneCollege of Liberal Arts and Sciences, Portland State University, Portland, OR, USA.
Carla J BergMilken Institute School of Public Health, George Washington University, Washington, DC, USA.
Matthew E RossheimSchool of Public Health, University of North Texas Health Science Center, Fort Worth, TX, USA.
Noah C PeeriDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Kayla K TillettSchool of Public Health, University of North Texas Health Science Center, Fort Worth, TX, USA.
Dong-Chul SeoSchool of Public Health, Indiana University Bloomington, Bloomington, IN, USA.

Funding

Helping Everyone Achieve a LifeTime of Health - Future Addiction Scientist TrainingR25DA054015 · NIDA · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI OBASI, EZEMENARI M., REITZEL, LORRAINE R · 2021 to 2025
$1.0M
Feasibility of Leveraging the National PulsePoint CPR Responder Network to Facilitate Overdose Education and Naloxone DistributionR34DA058162 · NIDA · TRUSTEES OF INDIANA UNIVERSITY · PI AGLEY, JON · 2023 to 2025
$713k
NIDA NIH HHS R25DA054015NIDA NIH HHS R34DA058162US DHHS Office of Minority Health CPIMP221346
6 · The paper itself

Abstract

backgroundKratom is federally unregulated and is marketed as an opioid alternative despite limited evidence and known negative effects. Disparities in associations between opioid and kratom use may be partly attributed to race/ethnicity and sexual orientation given differences in marketing, use motives, and prescriber practices.

methodsData: 2021 nationally representative National Survey on Drug Use and Health among individuals aged 18 + . We used weighted logistic regression analyses to assess race/ethnicity and sexual orientation as moderators of associations between past-year opioid (1) use (total sample, n = 44,877) and (2) misuse and use disorder (among those with past-year opioid use, n = 10,398) and the outcome of kratom use (lifetime, past year).

results26.76% reported past-year opioid use, and among those, 12.20% and 7.54% reported past-year opioid misuse and use disorder, respectively; 1.72% and 0.67% had lifetime and past-year kratom use, respectively. Opioid use was positively associated with lifetime (aOR = 2.69, 95%CI = 1.98, 3.66) and past-year (aOR = 3.84, 95%CI = 2.50, 5.92) kratom use; associations among non-Hispanic Black and Hispanic (vs. non-Hispanic White) participants were weaker (p < 0.01). Among participants reporting past-year opioid use, misuse and use disorder were positively associated with lifetime (aOR DISCUSSION: We observed positive associations between opioid and kratom use, with potential disparities among certain racial/ethnic and sexual orientation groups. Research should examine the mechanisms contributing to these differences to inform prevention and intervention efforts.

Indexed as

Analgesics, OpioidEthnicityMitragynaOpioid-Related DisordersRacial GroupsSexual BehaviorAdolescentAdultFemaleHumansMaleMiddle AgedUnited StatesYoung AdultAnalgesics, OpioidDisparitiesKratomNovel psychoactive substancesOpioidRaceSexual orientation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.