Evidence map›Paper›PMID 39196479›Full record

Observational studyJournal of clinical monitoring and computing2025

A novel positive end-expiratory pressure titration using electrical impedance tomography in spontaneously breathing acute respiratory distress syndrome patients on mechanical ventilation: an observational study from the MaastrICCht cohort.

S J H Heines, S A M de Jongh, F H C de Jongh, R P J Segers, K M H Gilissen, I C C van der Horst, B C T van Bussel, D C J J Bergmans

Abstract readObservational Study
In one paragraph

Observational study in Journal of clinical monitoring and computing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

S J H Heines *Department of Intensive Care, Maastricht University Medical Center+, P. Debyelaan 25, P.O. Box 5800, Maastricht, 6202, AZ, The Netherlands. S.heines@mumc.nl.ORCID 0000-0001-7672-4177
S A M de Jongh *Department of Intensive Care, Maastricht University Medical Center+, P. Debyelaan 25, P.O. Box 5800, Maastricht, 6202, AZ, The Netherlands.ORCID 0000-0002-9394-2288
F H C de JonghDepartment of Pulmonology, Medisch Spectrum Twente, Enschede, The Netherlands.ORCID 0000-0002-6052-7504
R P J SegersDepartment of Intensive Care, Maastricht University Medical Center+, P. Debyelaan 25, P.O. Box 5800, Maastricht, 6202, AZ, The Netherlands.
K M H GilissenDepartment of Intensive Care, Maastricht University Medical Center+, P. Debyelaan 25, P.O. Box 5800, Maastricht, 6202, AZ, The Netherlands.
I C C van der HorstDepartment of Intensive Care, Maastricht University Medical Center+, P. Debyelaan 25, P.O. Box 5800, Maastricht, 6202, AZ, The Netherlands.ORCID 0000-0003-3891-8522
B C T van BusselDepartment of Intensive Care, Maastricht University Medical Center+, P. Debyelaan 25, P.O. Box 5800, Maastricht, 6202, AZ, The Netherlands.ORCID 0000-0003-1621-7848
D C J J BergmansDepartment of Intensive Care, Maastricht University Medical Center+, P. Debyelaan 25, P.O. Box 5800, Maastricht, 6202, AZ, The Netherlands.ORCID 0000-0002-4224-6426

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is no universally accepted method for positive end expiratory pressure (PEEP) titration approach for patients on spontaneous mechanical ventilation (SMV). Electrical impedance tomography (EIT) guided PEEP-titration has shown promising results in controlled mechanical ventilation (CMV), current implemented algorithm for PEEP titration (based on regional compliance measurements) is not applicable in SMV. Regional peak flow (RPF, defined as the highest inspiratory flow rate based on EIT at a certain PEEP level) is a new method for quantifying regional lung mechanics designed for SMV. The objective is to study whether RPF by EIT is a feasible method for PEEP titration during SMV. Single EIT measurements were performed in COVID-19 ARDS patients on SMV. Clinical (i.e., tidal volume, airway occlusion pressure, end-tidal CO

Indexed as

COVID-19Electric ImpedancePositive-Pressure RespirationRespiration, ArtificialRespiratory Distress SyndromeTomographyAdultAgedAlgorithmsCohort StudiesFemaleHumansLungMaleMiddle AgedRespiratory MechanicsAirway occlusion pressureARDSElectrical impedance tomographyPendelluftPositive end-expiratory pressureRegional peak flowSpontaneous ventilation

Identifiers

PMID39196479
PMCPMC11821668

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.