Evidence map›Paper›PMID 39196451›Full record

ArticleThe international journal of cardiovascular imaging2024

The impact of spinal anesthesia on cardiac function in euvolemic vascular surgery patients: insights from echocardiography and biomarkers.

Georgia Gkounti, Charalampos Loutradis, Myrto Tzimou, Christos Katsioulis, Vasileios Nevras, Apostolos G Pitoulias, Helena Argiriadou, Georgios Efthimiadis, Georgios A Pitoulias

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Article in The international journal of cardiovascular imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Georgia GkountiSecond Department of Surgery- Division of Vascular Surgery, Aristotle University of Thessaloniki, "G. Gennimatas" Hospital, Thessaloniki, Greece.
Charalampos LoutradisSecond Department of Surgery- Division of Vascular Surgery, Aristotle University of Thessaloniki, "G. Gennimatas" Hospital, Thessaloniki, Greece.
Myrto TzimouSecond Department of Surgery- Division of Vascular Surgery, Aristotle University of Thessaloniki, "G. Gennimatas" Hospital, Thessaloniki, Greece.
Christos KatsioulisSecond Department of Surgery- Division of Vascular Surgery, Aristotle University of Thessaloniki, "G. Gennimatas" Hospital, Thessaloniki, Greece. doctor@katsioulis-cardiology.eu.
Vasileios NevrasSecond Department of Surgery- Division of Vascular Surgery, Aristotle University of Thessaloniki, "G. Gennimatas" Hospital, Thessaloniki, Greece.
Apostolos G PitouliasSecond Department of Surgery- Division of Vascular Surgery, Aristotle University of Thessaloniki, "G. Gennimatas" Hospital, Thessaloniki, Greece.
Helena ArgiriadouSchool of Health Sciences, Faculty of Medicine, Department of Anesthesia and Intensive Care, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Georgios EfthimiadisSchool of Health Sciences, Faculty of Medicine, First Cardiology Department, Cardiomyopathies Center, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki, Greece.
Georgios A PitouliasSchool of Health Sciences, Faculty of Medicine, Second Department of Surgery - Division of Vascular Surgery, Aristotle University of Thessaloniki, "G. Gennimatas" Hospital, Thessaloniki, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Existing evidence of the effect of spinal anesthesia (SA) on cardiac systolic function is scarce and inconclusive. This study aimed to evaluate the effects induced by a single injection of SA for elective vascular surgery on left (LV) and right (RV) ventricular systolic performance using transthoracic echocardiography (TTE). A prospective study. Single-center study, university hospital. Adult patients undergoing elective vascular surgery with SA. During patients' evaluations fluid administration was targeted using arterial waveform monitoring. All patients underwent TTE studies before and after SA induction for the assessment of indices reflective of LV and RV systolic function. Blood samples were drawn to measure troponin and brain natriuretic peptide (BNP) levels. A total of 62 patients (88.7% males, 71.00 ± 9.42 years) were included in the study. The primary outcome was the difference before and after SA in LV ejection fraction (LVEF) and tricuspid annular plane systolic excursion (TAPSE). In total population, LVEF significantly increased after SA 53.07% [16.51]vs 53.86% [13.28]; p < 0.001). End-systolic volume (ESV, 69.50 [51.50] vs. 65.00 [29.50] ml; p < 0.001) decreased while stroke volume (SV) insignificantly increased (70.51 ± 16.70 vs. 73.00 ± 18.76 ml; p = 0.131) during SA. TAPSE remained unchanged (2.23 [0.56] vs. 2.25 [0.69] mm; p = 0.558). In patients with impaired compared to those with preserved LV systolic function, the changes evidenced in LVEF (7.49 ± 4.15 vs. 0.59 ± 2.79; p < 0.001), ESV (-18.13 ± 18.20 vs-1.53 ± 9.09; p < 0.001) and SV (8.71 ± 11.96 vs-1.43 ± 11.89; p = 0.002) were greater. This study provides evidence that SA in patients undergoing elective vascular surgery improved LV systolic function, while changes in RV systolic function are minimal.

Indexed as

Anesthesia, SpinalBiomarkersNatriuretic Peptide, BrainPredictive Value of TestsStroke VolumeVascular Surgical ProceduresVentricular Function, LeftVentricular Function, RightAgedAged, 80 and overElective Surgical ProceduresFemaleHumansMaleMiddle AgedProspective StudiesBiomarkersNatriuretic Peptide, BrainTroponinArterial waveform analysisCardiac systolic functionEchocardiographyElective vascular surgeryLeft ventricular ejection fractionSpinal anesthesia

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.