Evidence map›Paper›PMID 39196343›Full record

ReviewClinical research in cardiology : official journal of the German Cardiac Society2025

Echocardiographic assessment of left atrial appendage morphology and function-an expert proposal by the German Working Group of Cardiovascular Ultrasound.

Andreas Hagendorff, Stephan Stöbe, Andreas Helfen, Fabian Knebel, Ertunc Altiok, Stephan Beckmann, Tarek Bekfani, Thomas Binder, Aydan Ewers, Ali Hamadanchi and 14 more

Abstract readReview
In one paragraph

Review in Clinical research in cardiology : official journal of the German Cardiac Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Review
  3. Review
  4. Comparison of therapeutic strategies in patients presenting with left atrial thrombus despite oral anticoagulation.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Andreas HagendorffDepartment of Cardiology, University Hospital Leipzig AöR, Leipzig, Germany. Andreas.Hagendorff@medizin.uni-leipzig.de.ORCID http://orcid.org/0000-0001-6288-7565
Stephan StöbeDepartment of Cardiology, University Hospital Leipzig AöR, Leipzig, Germany.
Andreas HelfenDepartment of Kardiologie, Katholische St. Paulus Gesellschaft, St.-Marien-Hospital Lünen, Lünen, Germany.
Fabian KnebelDepartment of Internal Medicine II, Cardiology, Sana Klinikum Lichtenberg, Berlin, Germany.
Ertunc AltiokDepartment of Cardiology, Angiology, and Intensive Medicine, University Hospital Aachen, Aachen, Germany.
Stephan BeckmannPrivatpraxis Kardiologie, Beckmann Ehlers Und Partner, Berlin-Grunewald, Germany.
Tarek BekfaniDepartment of Cardiology and Angiology, University Hospital Magdeburg AöR, Magdeburg, Germany.
Thomas BinderDepartment of Cardiology, University Hospital AKH, Vienna, Austria.
Aydan EwersDepartment of Cardiology and Angiology, BG University Hospital Bergmannsheil, Bochum, Germany.
Ali HamadanchiDepartment of Cardiology, University of Jena, Jena, Germany.
Henrik Ten FreyhausDepartment of Internal Medicine III, Cardiology, University of Cologne, Cologne, Germany.
Thomas GroscheckDepartment of Cardiology and Angiology, University Hospital Magdeburg AöR, Magdeburg, Germany.
Dariush HaghiKardiologische Praxisklinik Ludwigshafen-Akademische Lehrpraxis of the University of Mannheim, Ludwigshafen, Germany.
Jan KnierimDepartment of Internal Medicine and Cardiology, Paulinenkrankenhaus Berlin, Berlin, Germany.
Sebastian KruckPraxis Für Kardiologie Cardio Centrum Ludwigsburg, Ludwigsburg, Germany.
Karsten LenkDepartment of Cardiology, University Hospital Leipzig AöR, Leipzig, Germany.
Nicolas MerkeDepartment of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Charité Berlin, Berlin, Germany.
Dietrich PfeifferKardiologische Praxis Berlin (Adlershof), Berlin, Germany.
Elena Romero DortaDepartment of Cardiology, Angiology and Intensive Care Medicine, University of Berlin, Deutsches Herzzentrum Charité Berlin, Campus Mitte, Berlin, Germany.
Tobias RufDepartment of Cardiology, Center of Cardiology, Heart Valve Center, University Medical Center Mainz, University of Mainz, Mainz, Germany.
Christoph SinningDepartment of Cardiology, University Heart and Vascular Center Hamburg, German Centre of Cardiovascular Research (DZHK), Hamburg, Germany.
Nina C WunderlichDepartment of Cardiology, Asklepios Klinik Langen, Langen, Germany.
Roland BrandtDepartment of Cardiology, Kerckhoff Klinik GmbH, Bad Nauheim, Germany.
Sebastian EwenDepartment Cardiology and Intensive Care Medicine, Schwarzwald-Baar Klinik, Villingen-Schwenningen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The left atrial appendage is a blind ending cardiac structure prone to blood stasis due to its morphology. This structure is a preferred region of thrombogenesis in relation to reduced myocardial contractility of the atrial wall. Blood stasis occurs primarily in low flow conditions. One of the tasks of echocardiography is the analysis of morphology and function of the left atrial appendage. The detection of thrombi by echocardiography is difficult and must be carried out thoroughly and carefully to avoid potential complications-especially in the context of rhythm control. The assessment of thromboembolic risk, especially in patients with unknown and presumed atrial fibrillation is a second challenge by characterizing atrial function and flow conditions in the left atrial appendage. Thus, this proposal focuses on the obvious problems of echocardiography when assessing left atrial appendage and the role of this method in planning a potential interventional closure of left atrial appendage.

Indexed as

Atrial AppendageAtrial FibrillationAtrial Function, LeftEchocardiographyEchocardiography, TransesophagealGermanyHumansThromboembolismAtrial fibrillationEchocardiographyLAA functionLAA interventionLAA morphologyLeft atrial appendage

Identifiers

PMID39196343
PMCPMC11772409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.