Evidence map›Paper›PMID 39196267›Full record

ArticleMicrobial genomics2024

Comparison of gene-by-gene and genome-wide short nucleotide sequence-based approaches to define the global population structure of

Alannah C King, Narender Kumar, Kate C Mellor, Paulina A Hawkins, Lesley McGee, Nicholas J Croucher, Stephen D Bentley, John A Lees, Stephanie W Lo

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbial genomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alannah C KingParasites and Microbes, The Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
Narender KumarParasites and Microbes, The Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
Kate C MellorParasites and Microbes, The Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
Paulina A HawkinsRollins School Public Health, Emory University, Atlanta, GA, USA.
Lesley McGeeEmory Global Health Institute, Emory University, Atlanta, GA, USA.
Nicholas J CroucherMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.
Stephen D BentleyParasites and Microbes, The Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
John A LeesEMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridge, UK.
Stephanie W LoParasites and Microbes, The Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Defining the population structure of a pathogen is a key part of epidemiology, as genomically related isolates are likely to share key clinical features such as antimicrobial resistance profiles and invasiveness. Multiple different methods are currently used to cluster together closely related genomes, potentially leading to inconsistency between studies. Here, we use a global dataset of 26 306

Indexed as

Genome, BacterialMultilocus Sequence TypingPhylogenyStreptococcus pneumoniaeCluster AnalysisGenomicsHumansepidemiologyMLSTpneumococcal genomicspopulation structureStreptococcus pneumoniaewhole genome sequencing

Identifiers

PMID39196267
PMCPMC11353345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.