Evidence map›Paper›PMID 39195776›Full record

Observational studyToxins2024

Real-World Observational Analysis of Clinical Characteristics and Treatment Patterns of Patients with Chronic Sialorrhea.

Michael A Hast, Amanda M Kong, Jenna Abdelhadi, Rohan Shah, Andrew Szendrey, Jordan Holmes

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael A HastMerz Therapeutics, Raleigh, NC 27615, USA.
Amanda M KongAetion, New York, NY 10001, USA.ORCID 0000-0002-6210-4185
Jenna AbdelhadiAetion, New York, NY 10001, USA.
Rohan ShahAetion, New York, NY 10001, USA.ORCID 0000-0002-6930-0605
Andrew SzendreyAetion, New York, NY 10001, USA.
Jordan HolmesMerz Therapeutics, Raleigh, NC 27615, USA.

Funding

Merz (Germany) N/A
6 · The paper itself

Abstract

Chronic sialorrhea is a condition characterized by excessive drooling, often associated with neurological and neuromuscular disorders such as Parkinson's disease, cerebral palsy, and stroke. Despite its prevalence, it remains underdiagnosed and poorly understood, leading to a lack of comprehensive data on patient demographics, clinical characteristics, and treatment patterns. This study aimed to help fill these existing gaps by analyzing real-world data using Optum's de-identified Clinformatics

Indexed as

Botulinum Toxins, Type ASialorrheaAdolescentAdultAgedAged, 80 and overChildChild, PreschoolCholinergic AntagonistsChronic DiseaseComorbidityFemaleHumansMaleMiddle AgedParkinson DiseaseBotulinum Toxins, Type ACholinergic AntagonistsincobotulinumtoxinAanticholinergicbotulinum toxincerebral palsyneurologic disordersParkinson’ssialorrheatreatment utilization

Identifiers

PMID39195776
PMCPMC11360601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.