Evidence map›Paper›PMID 39195769›Full record

ArticleToxins2024

Rattlesnake Crotalphine Analgesic Active on Tetrodotoxin-Sensitive Na

Aurélie Antunes, Philippe Robin, Gilles Mourier, Rémy Béroud, Michel De Waard, Denis Servent, Evelyne Benoit

Abstract read
In one paragraph

Article in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aurélie AntunesDépartement Médicaments et Technologies pour la Santé (DMTS), Institut des Sciences du Vivant Frédéric Joliot, Université Paris-Saclay, CEA, Service d'Ingénierie Moléculaire pour la Santé (SIMoS), EMR CNRS/CEA 9004, F-91191 Gif-sur-Yvette, France.
Philippe RobinDépartement Médicaments et Technologies pour la Santé (DMTS), Institut des Sciences du Vivant Frédéric Joliot, Université Paris-Saclay, CEA, Service d'Ingénierie Moléculaire pour la Santé (SIMoS), EMR CNRS/CEA 9004, F-91191 Gif-sur-Yvette, France.
Gilles MourierDépartement Médicaments et Technologies pour la Santé (DMTS), Institut des Sciences du Vivant Frédéric Joliot, Université Paris-Saclay, CEA, Service d'Ingénierie Moléculaire pour la Santé (SIMoS), EMR CNRS/CEA 9004, F-91191 Gif-sur-Yvette, France.
Rémy BéroudSmartox Biotechnology, F-38120 Saint-Egrève, France.
Michel De WaardSmartox Biotechnology, F-38120 Saint-Egrève, France.ORCID 0000-0002-2782-9615
Denis ServentDépartement Médicaments et Technologies pour la Santé (DMTS), Institut des Sciences du Vivant Frédéric Joliot, Université Paris-Saclay, CEA, Service d'Ingénierie Moléculaire pour la Santé (SIMoS), EMR CNRS/CEA 9004, F-91191 Gif-sur-Yvette, France.ORCID 0000-0002-0774-1691
Evelyne BenoitDépartement Médicaments et Technologies pour la Santé (DMTS), Institut des Sciences du Vivant Frédéric Joliot, Université Paris-Saclay, CEA, Service d'Ingénierie Moléculaire pour la Santé (SIMoS), EMR CNRS/CEA 9004, F-91191 Gif-sur-Yvette, France.ORCID 0000-0001-5501-0888

Funding

French Alternative Energies and Atomic Energy Commission (CEA) NoneFrench National Center for Scientific Research (CNRS) NoneSmartox Biotechnology None
6 · The paper itself

Abstract

Crotalphine is an analgesic peptide identified from the venom of the South American rattlesnake

Indexed as

AnalgesicsGanglia, SpinalNAV1.7 Voltage-Gated Sodium ChannelNeuronsTetrodotoxinAnimalsCells, CulturedCell SurvivalCrotalid VenomsCrotalusMaleMembrane PotentialsMicePeptidesSodium Channel BlockersAnalgesicsCrotalid VenomscrotalphineNAV1.7 Voltage-Gated Sodium ChannelPeptidesSodium Channel BlockersTetrodotoxincell viability assaycrotalphineelectrophysiologymouse dorsal root ganglion neuronsrattlesnake toxintetrodotoxin-sensitive Na+ channels

Identifiers

PMID39195769
PMCPMC11359915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.