Evidence map›Paper›PMID 39195768›Full record

ArticleToxins2024

Cell Penetrating Peptide Enhances the Aphidicidal Activity of Spider Venom-Derived Neurotoxin.

Wenxian Wu, Abid Ali, Jinbo Shen, Maozhi Ren, Yi Cai, Limei He

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenxian WuInstitute of Urban Agriculture, Chinese Academy of Agricultural Sciences, Chengdu Agricultural Science and Technology Center, Chengdu 610000, China.ORCID 0000-0002-9122-9796
Abid AliDepartment of Entomology, University of Agriculture Faisalabad, Faisalabad 38040, Pakistan.ORCID 0000-0003-3674-7811
Jinbo ShenState Key Laboratory of Subtropical Silviculture, Zhejiang A&F University, Hangzhou 310000, China.
Maozhi RenInstitute of Urban Agriculture, Chinese Academy of Agricultural Sciences, Chengdu Agricultural Science and Technology Center, Chengdu 610000, China.
Yi CaiCollege of Life Science, Sichuan Agricultural University, Ya'an 625000, China.
Limei HeInstitute of Urban Agriculture, Chinese Academy of Agricultural Sciences, Chengdu Agricultural Science and Technology Center, Chengdu 610000, China.ORCID 0000-0002-5055-746X

Funding

Sichuan Province Key R&D Program, Hong Kong, Macao and Taiwan Science and Technology Innovation Cooperation Project 2024YFHZ0347STI 2030-Major Projects 2022ZD04021
6 · The paper itself

Abstract

HxTx-Hv1h, a neurotoxic peptide derived from spider venom, has been developed for use in commercial biopesticide formulations. Cell Penetrating Peptides (CPPs) are short peptides that facilitate the translocation of various biomolecules across cellular membranes. Here, we evaluated the aphidicidal efficacy of a conjugated peptide, HxTx-Hv1h/CPP-1838, created by fusing HxTx-Hv1h with CPP-1838. Additionally, we aimed to establish a robust recombinant expression system for HxTx-Hv1h/CPP-1838. We successfully achieved the secretory production of HxTx-Hv1h, its fusion with

Indexed as

Cell-Penetrating PeptidesNeurotoxinsSpider VenomsAnimalsInsecticidesPlant LectinsCell-Penetrating PeptidesInsecticidesNeurotoxinsPlant LectinsSpider Venomsaphicidecell penetrating peptidefusion proteininsecticidal neurotoxinmulti-copy expression

Identifiers

PMID39195768
PMCPMC11360749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.