Evidence map›Paper›PMID 39195757›Full record

SynthesisToxins2024

The Effect of Botulinum Neurotoxin-A (BoNT-A) on Muscle Strength in Adult-Onset Neurological Conditions with Focal Muscle Spasticity: A Systematic Review.

Renée Gill, Megan Banky, Zonghan Yang, Pablo Medina Mena, Chi Ching Angie Woo, Adam Bryant, John Olver, Elizabeth Moore, Gavin Williams

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Renée GillDepartment of Physiotherapy, Epworth Rehabilitation Epworth Healthcare Richmond, Melbourne 3121, Australia.ORCID 0000-0001-6577-3256
Megan BankyDepartment of Physiotherapy, Epworth Rehabilitation Epworth Healthcare Richmond, Melbourne 3121, Australia.
Zonghan YangSchool of Physiotherapy, The University of Melbourne, Parkville, Melbourne 3000, Australia.
Pablo Medina MenaDepartment of Physiotherapy, Epworth Rehabilitation Epworth Healthcare Richmond, Melbourne 3121, Australia.
Chi Ching Angie WooDepartment of Physiotherapy, Epworth Rehabilitation Epworth Healthcare Richmond, Melbourne 3121, Australia.
Adam BryantSchool of Physiotherapy, The University of Melbourne, Parkville, Melbourne 3000, Australia.
John OlverDepartment of Physiotherapy, Epworth Rehabilitation Epworth Healthcare Richmond, Melbourne 3121, Australia.ORCID 0000-0001-7069-1191
Elizabeth MooreDepartment of Physiotherapy, Epworth Rehabilitation Epworth Healthcare Richmond, Melbourne 3121, Australia.
Gavin WilliamsDepartment of Physiotherapy, Epworth Rehabilitation Epworth Healthcare Richmond, Melbourne 3121, Australia.

Funding

Andrew Dobbyn and Stephanie Margolin Scholarship from the Epworth Medical Foundation NAPhysiotherapy Research at Epworth Rehabilitation (PrOsPER) Foundation NA
6 · The paper itself

Abstract

Botulinum neurotoxin-A (BoNT-A) injections are effective for focal spasticity. However, the impact on muscle strength is not established. This study aimed to investigate the effect of BoNT-A injections on muscle strength in adult neurological conditions. Studies were included if they were Randomised Controlled Trials (RCTs), non-RCTs, or cohort studies (

Indexed as

Botulinum Toxins, Type AMuscle SpasticityMuscle StrengthNeuromuscular AgentsAdultHumansMuscle, SkeletalNervous System DiseasesBotulinum Toxins, Type ANeuromuscular Agentsbotulinum toxindynamometerlower limbMedical Research Council scalemuscle spasticitymuscle strengthupper limb

Identifiers

PMID39195757
PMCPMC11359732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.