Evidence map›Paper›PMID 39195652›Full record

ArticleToxics2024

Predictors of Serotonin Syndrome in Acute Poisoning with 5-Hydroxytryptamine Modulators.

Asmaa F Sharif, Mubarak Nasir M Almulhim, Hadi Mohamed A Almosabeh, Mohammed Essam A Alshammasy, Ali Mohammed A Aljeshi, Taher Mohammed A Mufti, Shahd AlNasser, Khalid A Al-Mulhim, Yousef A AlMubarak

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In one paragraph

Article in Toxics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Asmaa F SharifDepartment of Clinical Medical Sciences, College of Medicine, Dar AL-Uloom University, Al Falah, Riyadh 13314, Saudi Arabia.ORCID 0000-0002-6104-562X
Mubarak Nasir M AlmulhimCollege of Medicine, Dar AL-Uloom University, Al Falah, Riyadh 13314, Saudi Arabia.ORCID 0009-0003-0341-7645
Hadi Mohamed A AlmosabehCollege of Medicine, Dar AL-Uloom University, Al Falah, Riyadh 13314, Saudi Arabia.ORCID 0009-0001-3232-4726
Mohammed Essam A AlshammasyCollege of Medicine, Dar AL-Uloom University, Al Falah, Riyadh 13314, Saudi Arabia.ORCID 0009-0001-0817-2881
Ali Mohammed A AljeshiCollege of Medicine, Dar AL-Uloom University, Al Falah, Riyadh 13314, Saudi Arabia.ORCID 0009-0008-2040-5036
Taher Mohammed A MuftiCollege of Medicine, Dar AL-Uloom University, Al Falah, Riyadh 13314, Saudi Arabia.
Shahd AlNasserSaudi Food and Drug Authority, Hittin, Riyadh 13513, Saudi Arabia.
Khalid A Al-MulhimEmergency Medicine Department, King Fahad Medical City, Sulimaniyah, Riyadh 12231, Saudi Arabia.
Yousef A AlMubarakEmergency Medicine Department, King Fahad Medical City, Sulimaniyah, Riyadh 12231, Saudi Arabia.

Funding

General Directorate of Scientific Research & Innovation, Dar Al Uloom University, through the Scientific Publishing Funding Program, Riyadh, Saudi Arabia. NA
6 · The paper itself

Abstract

5-Hydroxytryptamine (5-HT) modulators are commonly prescribed medications with potentially life-threatening outcomes, particularly serotonin syndrome (SS). Early prediction of SS is critical not only to avoid lethal drug combinations but also to initiate appropriate treatment. The present work aimed to recognize the significant predictors of SS through a retrospective cross-sectional study that was conducted among patients exposed to an overdose of 5-HT modulators and admitted to a poison control center where 112 patients were enrolled. Of them, 21 patients were diagnosed with SS, and 66.7% of patients with SS were exposed to long-term co-ingestion. There was a noticeable surge in SS between April and May, and 52.4% of patients who suffered from SS were admitted after suicidal exposure (

Indexed as

5-hydroxytryptophanHunter Serotonin Toxicity Criteriaselective serotonin re-uptake inhibitorsserotonergic drugsserotonin syndromeserotonin toxicity

Identifiers

PMID39195652
PMCPMC11360237

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.