Evidence map›Paper›PMID 39195641›Full record

ReviewToxics2024

Per- and Polyfluoroalkyl Substances (PFASs) and Their Potential Effects on Female Reproductive Diseases.

Yuqing Yi, Yang Feng, Yuechen Shi, Jiaming Xiao, Ming Liu, Ke Wang

Abstract readReview
In one paragraph

Review in Toxics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuqing YiDepartment of Clinical Nutrition, Second Affiliated Hospital of Dalian Medical University, Dalian 116027, China.
Yang FengDepartment of Clinical Nutrition, Second Affiliated Hospital of Dalian Medical University, Dalian 116027, China.
Yuechen ShiDepartment of Clinical Nutrition, Second Affiliated Hospital of Dalian Medical University, Dalian 116027, China.
Jiaming XiaoDepartment of Clinical Nutrition, Second Affiliated Hospital of Dalian Medical University, Dalian 116027, China.
Ming LiuDepartment of Clinical Nutrition, Second Affiliated Hospital of Dalian Medical University, Dalian 116027, China.
Ke WangDepartment of Clinical Nutrition, Second Affiliated Hospital of Dalian Medical University, Dalian 116027, China.

Funding

Department of Science and Technology of Liaoning Province No.2022-BS-248Second Affiliated Hospital of Dalian Medical University No.2022LCJSGC15
6 · The paper itself

Abstract

Per- and polyfluoroalkyl substances (PFASs) are a class of anthropogenic organic compounds widely present in the natural and human living environments. These emerging persistent pollutants can enter the human body through multiple channels, posing risks to human health. In particular, exposure to PFASs in women may cause a series of reproductive health hazards and infertility. Based on a review of the existing literature, this study preliminarily summarizes the effects of PFAS exposure on the occurrence and development of female reproductive endocrine diseases, such as polycystic ovary syndrome (PCOS), endometriosis, primary ovarian insufficiency (POI), and diminished ovarian reserve (DOR). Furthermore, we outline the relevant mechanisms through which PFASs interfere with the physiological function of the female ovary and finally highlight the role played by nutrients in reducing the reproductive health hazards caused by PFASs. It is worth noting that the physiological mechanisms of PFASs in the above diseases are still unclear. Therefore, it is necessary to further study the molecular mechanisms of PFASs in female reproductive diseases and the role of nutrients in this process.

Indexed as

diminished ovarian reserveemerging persistent pollutantsendometriosisfemale reproductive diseasesPFASspolycystic ovary syndromeprimary ovarian insufficiency

Identifiers

PMID39195641
PMCPMC11358978

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.