Evidence map›Paper›PMID 39195389›Full record

ArticleNanomaterials (Basel, Switzerland)2024

Synthesized

Silvana Alfei, Guendalina Zuccari, Francesca Bacchetti, Carola Torazza, Marco Milanese, Carlo Siciliano, Constantinos M Athanassopoulos, Gabriella Piatti, Anna Maria Schito

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Silvana AlfeiDepartment of Pharmacy, University of Genoa, Viale Cembrano, 16148 Genoa, Italy.ORCID 0000-0002-4630-4371
Guendalina ZuccariDepartment of Pharmacy, University of Genoa, Viale Cembrano, 16148 Genoa, Italy.ORCID 0000-0002-9868-6199
Francesca BacchettiDepartment of Pharmacy, University of Genoa, Viale Cembrano, 16148 Genoa, Italy.ORCID 0009-0002-0686-7062
Carola TorazzaDepartment of Pharmacy, University of Genoa, Viale Cembrano, 16148 Genoa, Italy.ORCID 0000-0003-2236-5142
Marco MilaneseDepartment of Pharmacy, University of Genoa, Viale Cembrano, 16148 Genoa, Italy.ORCID 0000-0003-3384-0666
Carlo SicilianoDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.ORCID 0000-0002-0584-219X
Constantinos M AthanassopoulosDepartment of Chemistry, University of Patras, University Campus Rio Achaias, 26504 Rio, Greece.ORCID 0000-0002-7549-1911
Gabriella PiattiDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Viale Benedetto XV, 6, 16132 Genova, Italy.
Anna Maria SchitoDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Viale Benedetto XV, 6, 16132 Genova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing emergence of multidrug-resistant (MDR) pathogens due to antibiotic misuse translates into obstinate infections with high morbidity and high-cost hospitalizations. To oppose these MDR superbugs, new antimicrobial options are necessary. Although both quaternary ammonium salts (QASs) and phosphonium salts (QPSs) possess antimicrobial effects, QPSs have been studied to a lesser extent. Recently, we successfully reported the bacteriostatic and cytotoxic effects of a triphenyl phosphonium salt against MDR isolates of the

Indexed as

cytotoxicity studiesmembranes permeabilizationMICs determinationmitochondria target bola-amphiphilesmultidrug resistant bacteriatime-killing experimentstriphenyl phosphonium salts

Identifiers

PMID39195389
PMCPMC11357385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.