Evidence map›Paper›PMID 39195316›Full record

ReviewCurrent oncology (Toronto, Ont.)2024

Lymph Node Metastasis in Gastrointestinal Carcinomas: A View from a Proteomics Perspective.

Vaishali Jain, Puja Sakhuja, Anil Kumar Agarwal, Ravi Sirdeshmukh, Fouzia Siraj, Poonam Gautam

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current oncology (Toronto, Ont.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vaishali JainIndian Council of Medical Research, National Institute of Pathology, New Delhi 110029, India.
Puja SakhujaGovind Ballabh Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi 110002, India.
Anil Kumar AgarwalGovind Ballabh Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi 110002, India.
Ravi SirdeshmukhFaculty of Health Sciences, Manipal Academy of Higher Education (MAHE), Manipal 576104, India.
Fouzia SirajIndian Council of Medical Research, National Institute of Pathology, New Delhi 110029, India.ORCID 0000-0001-7643-7936
Poonam GautamIndian Council of Medical Research, National Institute of Pathology, New Delhi 110029, India.ORCID 0000-0002-3804-6157

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymph node metastasis (LNM) is one of the major prognostic factors in human gastrointestinal carcinomas (GICs). The lymph node-positive patients have poorer survival than node-negative patients. LNM is directly associated with the recurrence and poor survival of patients with GICs. The early detection of LNM in patients and designing effective therapies to suppress LNM may significantly impact the survival of these patients. The rapid progress made in proteomic technologies could be successfully applied to identify molecular targets for cancers at high-throughput levels. LC-MS/MS analysis enables the identification of proteins involved in LN metastasis, which can be utilized for diagnostic and therapeutic applications. This review summarizes the studies on LN metastasis in GICs using proteomic approaches to date.

Indexed as

Gastrointestinal NeoplasmsLymphatic MetastasisProteomicsHumansgastrointestinal carcinomaslymph node metastasismicrometastasisproteomicssentinel lymph node

Identifiers

PMID39195316
PMCPMC11352871

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.