Evidence map›Paper›PMID 39195294›Full record

ReviewCurrent oncology (Toronto, Ont.)2024

Prostate-Specific Membrane Antigen Expression in Patients with Primary Prostate Cancer: Diagnostic and Prognostic Value in Positron Emission Tomography-Prostate-Specific Membrane Antigen.

Omar Tayara, Sławomir Poletajew, Wojciech Malewski, Jolanta Kunikowska, Kacper Pełka, Piotr Kryst, Łukasz Nyk

Abstract readReview
In one paragraph

Review in Current oncology (Toronto, Ont.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. A Framework for Autonomous AI-Driven Drug Discovery.bioRxiv : the preprint server for biology · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Omar TayaraSecond Department of Urology, Centre of Postgraduate Medical Education, 02-511 Warsaw, Poland.ORCID 0000-0001-7212-9266
Sławomir PoletajewSecond Department of Urology, Centre of Postgraduate Medical Education, 02-511 Warsaw, Poland.ORCID 0000-0001-7664-9816
Wojciech MalewskiSecond Department of Urology, Centre of Postgraduate Medical Education, 02-511 Warsaw, Poland.
Jolanta KunikowskaDepartment of Nuclear Medicine, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0002-7434-6720
Kacper PełkaDepartment of Nuclear Medicine, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0002-4679-9669
Piotr KrystSecond Department of Urology, Centre of Postgraduate Medical Education, 02-511 Warsaw, Poland.ORCID 0000-0003-2551-0296
Łukasz NykSecond Department of Urology, Centre of Postgraduate Medical Education, 02-511 Warsaw, Poland.ORCID 0000-0001-6502-1484

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer represents a significant public health challenge, with its management requiring precise diagnostic and prognostic tools. Prostate-specific membrane antigen (PSMA), a cell surface enzyme overexpressed in prostate cancer cells, has emerged as a pivotal biomarker. PSMA's ability to increase the sensitivity of PET imaging has revolutionized its application in the clinical management of prostate cancer. The advancements in PET-PSMA imaging technologies and methodologies, including the development of PSMA-targeted radiotracers and optimized imaging protocols, led to diagnostic accuracy and clinical utility across different stages of prostate cancer. This highlights its superiority in staging and its comparative effectiveness against conventional imaging modalities. This paper analyzes the impact of PET-PSMA on prostate cancer management, discussing the existing challenges and suggesting future research directions. The integration of recent studies and reviews underscores the evolving understanding of PET-PSMA imaging, marking its significant but still expanding role in clinical practice. This comprehensive review serves as a crucial resource for clinicians and researchers involved in the multifaceted domains of prostate cancer diagnosis, treatment, and management.

Indexed as

Positron-Emission TomographyProstatic NeoplasmsAntigens, SurfaceBiomarkers, TumorGlutamate Carboxypeptidase IIHumansMalePrognosisAntigens, SurfaceBiomarkers, TumorFOLH1 protein, humanGlutamate Carboxypeptidase II18F-fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid (DCFPy)Carbon-11 Choline (C-11 Choline)computed tomography (CT)Food and Drug Administration (FDA)Gleason score (GS)magnetic resonance imaging (MRI)positron emission tomography (PET)prostate-specific antigen (PSA)prostate-specific membrane antigen (PSMA)radiomic features (RF)seminal vesicle invasion (SVI)

Identifiers

PMID39195294
PMCPMC11352643

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.