Evidence map›Paper›PMID 39195273›Full record

ArticleCells2024

Anticancer Activity of Benzo[

João Carlos Canossa Ferreira, M Sameiro T Gonçalves, Ana Preto, Maria João Sousa

Abstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

João Carlos Canossa FerreiraCentre of Molecular and Environmental Biology (CBMA), Department of Biology, University of Minho, Campus of Gualtar, 4710-057 Braga, Portugal.
M Sameiro T GonçalvesCentre of Chemistry (CQUM), Department of Chemistry, University of Minho, Campus of Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0003-2048-1190
Ana PretoCentre of Molecular and Environmental Biology (CBMA), Department of Biology, University of Minho, Campus of Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0002-7302-0630
Maria João SousaCentre of Molecular and Environmental Biology (CBMA), Department of Biology, University of Minho, Campus of Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0001-9424-4150

Funding

Fundação para a Ciência e Tecnologia COVID/BD/151978/2021Fundação para a Ciência e Tecnologia PTDC/QUIQIN/28662/2017Fundação para a Ciência e Tecnologia SFRH/BD/133207/2017Fundação para a Ciência e Tecnologia UID/BIA/04050/2020Fundação para a Ciência e Tecnologia UID/QUI/0686/2021
6 · The paper itself

Abstract

Specific cancer therapy remains a problem to be solved. Breast and colorectal cancer are among the cancers with the highest prevalence and mortality rates. Although there are some therapeutic options, there are still few effective agents for those cancers, which constitutes a clinical problem that requires further research efforts. Lysosomes play an important role in cancer cells' survival, and targeting lysosomes has gained increased interest. In recent years, our team has been synthetizing and testing novel benzo[

Indexed as

Antineoplastic AgentsCell ProliferationLysosomesOxazinesCell Line, TumorCell MovementCell SurvivalHumansMCF-7 CellsReactive Oxygen SpeciesAntineoplastic AgentsOxazinesphenoxazineReactive Oxygen Speciesanticancer drugbenzo[a]phenoxazinebreast cancercolorectal cancerlysosome membrane permeabilizationNile Blue analogue

Identifiers

PMID39195273
PMCPMC11352945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.