Evidence map›Paper›PMID 39195205›Full record

ArticleCells2024

Synergistic Activity of Cefiderocol in Combination with Avibactam, Sulbactam or Tazobactam against Carbapenem-Resistant Gram-Negative Bacteria.

Russell E Lewis, Marta Palombo, Erica Diani, Benedetta Secci, Davide Gibellini, Paolo Gaibani

Abstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Sulbactam-durlobactam and cefiderocol combination treatment ofAntimicrobial agents and chemotherapy · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Sulbactam for carbapenem-resistantJAC-antimicrobial resistance · 2025
    Review
  9. Revisiting the Metallo-International journal of microbiology · 2025
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Russell E LewisDepartment of Molecular Medicine, University of Padova, 35122 Padova, Italy.
Marta PalomboIRCCS Azienda Ospedaliero, Universitaria di Bologna, 40135 Bologna, Italy.
Erica DianiDepartment of Diagnostic and Public Health, Microbiology Section, Verona University, 37134 Verona, Italy.ORCID 0000-0002-1373-7533
Benedetta SecciIRCCS Azienda Ospedaliero, Universitaria di Bologna, 40135 Bologna, Italy.
Davide GibelliniDepartment of Diagnostic and Public Health, Microbiology Section, Verona University, 37134 Verona, Italy.
Paolo GaibaniDepartment of Diagnostic and Public Health, Microbiology Section, Verona University, 37134 Verona, Italy.ORCID 0000-0003-3791-8635

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the activity of cefiderocol/β-lactamase inhibitor combinations against clinical strains with different susceptibility profiles to cefiderocol to explore the potentiality of antibiotic combinations as a strategy to contain the major public health problem of multidrug-resistant (MDR) pathogens. Specifically, we evaluated the synergistic activity of cefiderocol with avibactam, sulbactam, or tazobactam on three of the most "Critical Priority" group of MDR bacteria (carbapenem-resistant

Indexed as

Anti-Bacterial AgentsAzabicyclo CompoundsCefiderocolCephalosporinsDrug SynergismGram-Negative BacteriaMicrobial Sensitivity TestsSulbactamTazobactamAcinetobacter baumanniibeta-Lactamase InhibitorsCarbapenemsDrug CombinationsDrug Resistance, Multiple, BacterialHumansPseudomonas aeruginosaAnti-Bacterial AgentsavibactamAzabicyclo Compoundsbeta-Lactamase InhibitorsCarbapenemsCefiderocolCephalosporinsDrug CombinationsSulbactamTazobactamcarbapenem-resistant Acinetobacter baumanniicarbapenem-resistant Enterobacterialescarbapenem-resistant Pseudomonas aeruginosacefiderocol/avibactamcefiderocol/sulbactamcefiderocol/tazobactam

Identifiers

PMID39195205
PMCPMC11352988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.