Evidence map›Paper›PMID 39195173›Full record

ArticleDiseases (Basel, Switzerland)2024

Evaluation of the Effectiveness of Combined Treatment with Intravaginal Diazepam and Pelvic Floor Rehabilitation in Patients with Vulvodynia by Ultrasound Monitoring of Biometric Parameters of Pelvic Muscles: A Pilot Study.

Lucia Merlino, Enrico Ciminello, Agnese Immacolata Volpicelli, Stefano Tillier, Marianna Francesca Pasquali, Mattia Dominoni, Barbara Gardella, Roberto Senatori, Barbara Dionisi, Maria Grazia Piccioni

Abstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lucia MerlinoDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-4281-8308
Enrico CiminelloItalian National Institute of Health, 00161 Rome, Italy.
Agnese Immacolata VolpicelliSchool of Gynecology and Obstetrics, University of Eastern Piedmont, 28100 Novara, Italy.
Stefano TillierSchool of Gynecology and Obstetrics, University of Eastern Piedmont, 28100 Novara, Italy.
Marianna Francesca PasqualiDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.
Mattia DominoniDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-6322-607X
Barbara GardellaDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-0812-8995
Roberto SenatoriVulvar Pathology Study Center, 00161 Roma, Italy.ORCID 0000-0001-5631-9502
Barbara DionisiVulvar Pathology Study Center, 00161 Roma, Italy.
Maria Grazia PiccioniDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 00161 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Vulvodynia is characterized by vulvar pain for at least three months and may have related variables, one of these being pelvic floor hypertonus. The purpose of this study was to compare the therapeutic effectiveness of two weekly sessions of pelvic floor rehabilitation and 5 mg of vaginal diazepam daily vs. pelvic floor rehabilitation alone in individuals with vulvodynia. (2) Methods: A single-center, not-blind, randomized study enrolled 20 vulvodynic patients: A total of 10 were treated with dual therapy (intravaginal diazepam and pelvic floor rehabilitation), and 10 were treated with only pelvic floor rehabilitation. All of them underwent a pelvic floor ultrasound examination and VAS pain and Marinoff scale assessments before the beginning of therapy as well as three and six months later. (3) Results: The elevator plate angle ranged from 8.2 to 9.55 (

Indexed as

painpelvis floorrehabilitationvulvodynia

Identifiers

PMID39195173
PMCPMC11354116

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.