Evidence map›Paper›PMID 39195151›Full record

ReviewJournal of cardiovascular development and disease2024

Antiarrhythmic Drug Use in Pregnancy: Considerations and Safety Profiles.

Marco Valerio Mariani, Nicola Pierucci, Vincenzo Mirco La Fazia, Pietro Cipollone, Marco Micillo, Andrea D'Amato, Francesca Fanisio, Giuseppe Ammirati, Nethuja Salagundla, Carlo Lavalle and 1 more

Abstract readReview
In one paragraph

Review in Journal of cardiovascular development and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marco Valerio MarianiDepartment of Clinical Internal Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-9480-1209
Nicola PierucciDepartment of Clinical Internal Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-5985-4081
Vincenzo Mirco La FaziaTexas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin, TX 78705, USA.ORCID 0000-0001-7548-4685
Pietro CipolloneDepartment of Clinical Internal Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Marco MicilloCardiology Department, S. Anna University Hospital, 44122 Ferrara, Italy.ORCID 0000-0002-9122-9534
Andrea D'AmatoDepartment of Clinical Internal Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Francesca FanisioDivision of Cardiology, Policlinico Casilino, 00169 Rome, Italy.ORCID 0000-0002-1488-7015
Giuseppe AmmiratiDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80138 Naples, Italy.ORCID 0000-0002-7440-1793
Nethuja SalagundlaTexas Health Arlington Memorial Hospital, Dallas, TX 76012, USA.
Carlo LavalleDepartment of Clinical Internal Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Marco Alfonso PerroneDivision of Cardiology and CardioLab, Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-0511-2621

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnancy entails notable physiological alterations and hormonal fluctuations that affect the well-being of both the fetus and the mother. Cardiovascular events and arrhythmias are a major concern during pregnancy, especially in women with comorbidities or a history of arrhythmias. This paper provides an overview of the prevalence, therapies, and prognoses of different types of arrhythmias during pregnancy. The administration of antiarrhythmic drugs (AADs) during pregnancy demands careful consideration because of their possible effect on the mother and fetus. AADs can cross the placenta or be present in breast milk, potentially leading to adverse effects such as teratogenicity, growth restriction, or premature birth. The safety profiles of different classes of AADs are discussed. Individualized treatment approaches and close monitoring of pregnant women prescribed AADs are essential to ensure optimal maternal and fetal outcomes.

Indexed as

antiarrhythmic drugsarrhythmiapregnancy

Identifiers

PMID39195151
PMCPMC11354975

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.