Evidence map›Paper›PMID 39195093›Full record

ArticleDentistry journal2024

Evaluation of Cytotoxicity of the Dental Materials TheraCal LC, TheraCal PT, ApaCal ART and Biodentine Used in Vital Pulp Therapy: In Vitro Study.

Barbora Novotná, Pavel Holík, Yuliya Morozova, Matej Rosa, Adéla Galandáková, Kateřina Langová

Abstract read
In one paragraph

Article in Dentistry journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Barbora NovotnáInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University and Faculty Hospital Olomouc, Palackého 12, 779 00 Olomouc, Czech Republic.ORCID 0000-0001-8788-4272
Pavel HolíkInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University and Faculty Hospital Olomouc, Palackého 12, 779 00 Olomouc, Czech Republic.
Yuliya MorozovaInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University and Faculty Hospital Olomouc, Palackého 12, 779 00 Olomouc, Czech Republic.
Matej RosaInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University and Faculty Hospital Olomouc, Palackého 12, 779 00 Olomouc, Czech Republic.ORCID 0000-0003-0882-8438
Adéla GalandákováDepartment of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech Republic.
Kateřina LangováDepartment of Medical Biophysics, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech Republic.

Funding

Palacký University Olomouc IGA_LF_2024_008
6 · The paper itself

Abstract

(1) Background: The aim of this study was to compare the cytotoxicity of selected resin-modified materials used in direct contact with the dental pulp (TheraCal LC, TheraCal PT, and ApaCal ART) with calcium silicate cement (Biodentine). (2) Methods: The mouse fibroblast Balb/3T3 cell line and the extracts of tested materials in four concentrations were used for the testing. An MTT assay was performed in three independent experiments with six replicates for each concentration of tested material. The cell viability (%) and cytotoxicity were expressed (cytotoxic effect is considered in cases where the cell viability is lower than 70%). The mean of the cell viability and the standard deviation were expressed for each material at all concentrations. ANOVA and Dunnet's post hoc tests were used for the statistical analysis. All of these tests were performed at the 0.05 significance level. (3) Results: At all concentrations, the cell viability was statistically significantly lower (

Indexed as

calcium phosphatecalcium silicatecytotoxicitydeep cariesdental pulpMTT assayresin-modifiedvital pulp treatment

Identifiers

PMID39195093
PMCPMC11352889

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.