Evidence map›Paper›PMID 39195007›Full record

ArticleInfectious disease reports2024

A Retrospective Study: Evaluating the Impact of the COVID-19 Pandemic on Inflammatory Markers in Hospitalized Patients.

Elmoeiz A Elnagi, Thekra N Al-Maqati, Rawan M Maawadh, Salma AlBahrani, Faisal Salem Al Khalaf, Faisal M Alzahrani, Wael Nazzal, Maha Alanazi, Abdullah S Abdali, Amjad Saleh Al Atawi and 5 more

Abstract read
In one paragraph

Article in Infectious disease reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Elmoeiz A ElnagiDepartment of Clinical Laboratory Sciences, Prince Sultan Military College of Health Sciences, Dhahran 34313, Saudi Arabia.
Thekra N Al-MaqatiDepartment of Clinical Laboratory Sciences, Prince Sultan Military College of Health Sciences, Dhahran 34313, Saudi Arabia.ORCID 0000-0001-5705-2053
Rawan M MaawadhDepartment of Clinical Laboratory Sciences, Prince Sultan Military College of Health Sciences, Dhahran 34313, Saudi Arabia.ORCID 0000-0003-0599-9450
Salma AlBahraniInternal Medicine Department, King Fahad Military Medical Complex, Dhahran 34313, Saudi Arabia.
Faisal Salem Al KhalafDepartment of Clinical Laboratory Sciences, Prince Sultan Military College of Health Sciences, Dhahran 34313, Saudi Arabia.ORCID 0009-0007-2493-8342
Faisal M AlzahraniDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi Arabia.ORCID 0000-0003-4425-6502
Wael NazzalDepartment of Obstetrics and Gynecology, King Fahad Military Medical Complex, Dhahran 34313, Saudi Arabia.
Maha AlanaziDepartment of Pathology and Laboratory Medicine, King Fahad Specialist Hospital, Dammam 32253, Saudi Arabia.ORCID 0000-0002-2160-0799
Abdullah S AbdaliDepartment of Clinical Laboratory Sciences, Prince Sultan Military College of Health Sciences, Dhahran 34313, Saudi Arabia.
Amjad Saleh Al AtawiDepartment of Clinical Laboratory Sciences, Prince Sultan Military College of Health Sciences, Dhahran 34313, Saudi Arabia.
Lamiaa H Al-JameaDepartment of Medical Laboratory, King Fahad Military Medical Complex, Dhahran 34313, Saudi Arabia.ORCID 0000-0003-2638-3751
Ahmad Mohammad AlshehriDepartment of Medical Laboratory, King Fahad Military Medical Complex, Dhahran 34313, Saudi Arabia.ORCID 0009-0001-0817-6284
Adnan Awad ALshammariDepartment of Medical Laboratory, King Fahad Military Medical Complex, Dhahran 34313, Saudi Arabia.
Rania Saad SulimanDepartment of Clinical Laboratory Sciences, Prince Sultan Military College of Health Sciences, Dhahran 34313, Saudi Arabia.
Ibrahim Al BassamPlastic and Reconstructive Surgery Unit, King Fahd Military Medical Complex, Dhahran 34313, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic has had a significant impact globally, and understanding the relationship between inflammatory markers and disease progression is crucial for effective management. This retrospective study aimed to examine the association between various inflammatory markers, such as C-reactive protein (CRP), the erythrocyte sedimentation rate (ESR), lactate dehydrogenase (LDH), D-dimer, ferritin, and procalcitonin (PCT), and the characteristics of disease progression and outcomes in individuals affected by COVID-19.

methodsThis study collected raw data from 470 patients who tested positive for SARS-CoV-2 using RT-PCR.

resultsThe logistic regression analysis revealed that elevated LDH levels were associated with male gender, ICU admission, low oxygen saturation (O

conclusionThis study highlights the importance of monitoring key inflammatory markers, such as LDH, D-dimer, and ferritin, as they are significantly associated with the severity of COVID-19 illness. These findings can inform clinical decision-making and guide the development of targeted interventions to improve patient outcomes.

Indexed as

CRPcytokines stormD-dimerESRferritinLDHPCT

Identifiers

PMID39195007
PMCPMC11353753

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.