Evidence map›Paper›PMID 39194644›Full record

ArticleJournal of functional biomaterials2024

Vaginal Ovule Loaded with Bismuth Lipophilic Nanoparticles and Cetylpyridinium Chloride Inhibits Human Cervical Carcinoma and

Claudio Cabral-Romero, Rene Hernández-Delgadillo, Jesús Alejandro Torres-Betancourt, Claudia María García-Cuellar, Yesennia Sánchez-Pérez, Juan Manuel Solis-Soto, Irene Meester, Nayely Pineda-Aguilar, Sergio Eduardo Nakagoshi-Cepeda, Juan Valerio Cauich-Rodríguez and 1 more

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Claudio Cabral-RomeroLaboratorio de Biología Molecular, Facultad de Odontología, Universidad Autónoma de Nuevo León (UANL), Monterrey 66455, Nuevo León, Mexico.ORCID 0000-0002-2657-0111
Rene Hernández-DelgadilloLaboratorio de Biología Molecular, Facultad de Odontología, Universidad Autónoma de Nuevo León (UANL), Monterrey 66455, Nuevo León, Mexico.
Jesús Alejandro Torres-BetancourtLaboratorio de Biología Molecular, Facultad de Odontología, Universidad Autónoma de Nuevo León (UANL), Monterrey 66455, Nuevo León, Mexico.
Claudia María García-CuellarSubdirección de Investigación Básica, Instituto Nacional de Cancerología, Ciudad de México 14080, Distrito Federal, Mexico.ORCID 0000-0001-8080-5797
Yesennia Sánchez-PérezSubdirección de Investigación Básica, Instituto Nacional de Cancerología, Ciudad de México 14080, Distrito Federal, Mexico.ORCID 0000-0003-0103-9188
Juan Manuel Solis-SotoLaboratorio de Biología Molecular, Facultad de Odontología, Universidad Autónoma de Nuevo León (UANL), Monterrey 66455, Nuevo León, Mexico.
Irene MeesterDepartamento de Ciencias Básicas, Universidad de Monterrey, San Pedro Garza García 66238, Nuevo León, Mexico.ORCID 0000-0002-0609-3207
Nayely Pineda-AguilarCentro de Investigación en Materiales Avanzados, S.C. (CIMAV), Subsede Monterrey, PIIT, Apodaca 66628, Nuevo León, Mexico.ORCID 0000-0002-3894-597X
Sergio Eduardo Nakagoshi-CepedaLaboratorio de Biología Molecular, Facultad de Odontología, Universidad Autónoma de Nuevo León (UANL), Monterrey 66455, Nuevo León, Mexico.
Juan Valerio Cauich-RodríguezCentro de Investigación Científica de Yucatán, Unidad de Materiales, Mérida 97205, Yucatán, Mexico.ORCID 0000-0003-0809-7794
María Argelia Akemi Nakagoshi-CepedaLaboratorio de Biología Molecular, Facultad de Odontología, Universidad Autónoma de Nuevo León (UANL), Monterrey 66455, Nuevo León, Mexico.

Funding

This study was supported by CONACHyT for the Sectorial Fund for Education Research A1-S-20148
6 · The paper itself

Abstract

Bismuth lipophilic nanoparticles (BisBAL NPs) and cetylpyridinium chloride (CPC) are antineoplastic and antimicrobial in vitro. As a next pre-clinical step, a clinically viable dosage form for vaginal application was developed. Compendial pharmacopeial tests (mass uniformity, disintegration, and compressive mechanics) and inductively coupled plasma optical emission spectroscopy were conducted on in-house developed glycerinated gelatin (60:15

Indexed as

antitumor and antimycotic activitybismuth lipophilic nanoparticles (BisBAL NPs)cetylpyridinium chloridehuman cervical carcinomatopical treatmentvaginal ovule

Identifiers

PMID39194644
PMCPMC11355390

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.