Evidence map›Paper›PMID 39194445›Full record

ArticleBiomimetics (Basel, Switzerland)2024

Effects of Aging on New Bone Regeneration in a Mandibular Bone Defect in a Rat Model.

Jung Ho Park, Jong Hoon Park, Hwa Young Yu, Hyun Seok

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jung Ho ParkDepartment of Orl and Maxillofacial Surgery, School of Dentistry, Jeonbuk National University, Jeonju 54896, Republic of Korea.
Jong Hoon ParkDepartment of Orl and Maxillofacial Surgery, School of Dentistry, Jeonbuk National University, Jeonju 54896, Republic of Korea.
Hwa Young YuDepartment of Oral Pathology, School of Dentistry, Jeonbuk National University, Jeonju 54896, Republic of Korea.
Hyun SeokDepartment of Orl and Maxillofacial Surgery, School of Dentistry, Jeonbuk National University, Jeonju 54896, Republic of Korea.ORCID 0000-0002-5278-3807

Funding

National Research Foundation of Korea NRF-2021R1F1A1058657
6 · The paper itself

Abstract

The effects of aging on the healing capacity of maxillofacial bone defects have not been studied. The aim of this study was to evaluate the effects of aging on the regeneration of round bony defects in the mandible. We created a round-shaped bony defect in the mandibular angle area in rats of different ages (2-[2 M], 10-[10 M], and 20-month-old [20 M]) and evaluated new bone regeneration in these groups. Changes in bone turnover markers such as alkaline phosphatase, procollagen type I N-terminal propeptide (PINP), cross-linked C-telopeptide of type I collagen, and tartrate-resistant acid phosphatase 5B (TRAP5b) were investigated. The bone volume/total volume and bone mineral density of the 20 M group were significantly higher than those of the 2 M group (

Indexed as

agingmandiblemaxillofacial bonenew bone regeneration

Identifiers

PMID39194445
PMCPMC11351823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.