Evidence map›Paper›PMID 39194263›Full record

ArticleAntimicrobial agents and chemotherapy2024

Onametostat, a PfPRMT5 inhibitor, exhibits antimalarial activity to

Hui Min, Amuza Byaruhanga Lucky, Jesper J Madsen, Anongruk Chim-Ong, Xiaolian Li, Liwang Cui, Jun Miao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hui Min *Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Amuza Byaruhanga Lucky *Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Jesper J MadsenCenter for Global Health and Infectious Diseases Research, College of Public Health, University of South Florida, Tampa, Florida, USA.
Anongruk Chim-OngDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Xiaolian LiDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Liwang CuiDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.ORCID 0000-0002-8338-1974
Jun MiaoDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.ORCID 0000-0001-9374-6749

Funding

Southeast Asia Malaria Research CenterU19AI089672 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CUI, LIWANG · 2010 to 2023
$28.9M
Molecular Mechanisms of Artemisinin ResistanceR01AI128940 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CUI, LIWANG · 2017 to 2021
$971k
Development of CRISPR/dCas-based epigenetic gene regulation tools in malaria parasiteR21AI149202 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI MIAO, JUN · 2020 to 2021
$411k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI128940HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R21AI149202HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) U19AI089672NIAID NIH HHS R01 AI128940NIAID NIH HHS R21 AI149202NIAID NIH HHS U19 AI089672USF | Morsani College of Medicine (MCOM) startup fund
6 · The paper itself

Abstract

Protein arginine methyltransferases (PRMTs) play critical roles in

Indexed as

AntimalarialsPlasmodium falciparumProtein-Arginine N-MethyltransferasesEnzyme InhibitorsErythrocytesHistonesHumansInhibitory Concentration 50Malaria, FalciparumProtozoan ProteinsAntimalarialsEnzyme InhibitorsHistonesProtein-Arginine N-MethyltransferasesProtozoan Proteinsantimalarialsarginine methylationPlasmodium falciparumPRMT

Identifiers

PMID39194263
PMCPMC11459956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.