Evidence map›Paper›PMID 39194245›Full record

ArticleJournal of virology2024

Influenza virus antibodies inhibit antigen-specific

Eileen Goodwin, James S Gibbs, Jonathan W Yewdell, Laurence C Eisenlohr, Scott E Hensley

Abstract read
In one paragraph

Article in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Eileen GoodwinDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
James S GibbsLaboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Jonathan W YewdellLaboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0002-3826-1906
Laurence C EisenlohrDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Scott E HensleyDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-2928-7506

Funding

NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00015 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HENSLEY, SCOTT · 2021 to 2025
$50.7M
Impact of prior influenza exposures on antibody repertoires to new viral strainsR01AI108686 · NIAID · WISTAR INSTITUTE · PI HENSLEY, SCOTT ERIC · 2014 to 2022
$3.7M
HHS | National Institutes of Health (NIH) 1R01AI108686NIAID NIH HHS 75N93021C00015NIAID NIH HHS R01 AI108686
6 · The paper itself

Abstract

Antibody responses to influenza vaccines tend to be focused on epitopes encountered during prior influenza exposures, with little production of

Indexed as

Antibodies, MonoclonalAntibodies, ViralB-LymphocytesHemagglutinin Glycoproteins, Influenza VirusInfluenza VaccinesAnimalsAntibody FormationEpitopesFemaleImmunoglobulin GMiceMice, Inbred BALB CNeuraminidaseOrthomyxoviridae InfectionsAntibodies, MonoclonalAntibodies, ViralEpitopesHemagglutinin Glycoproteins, Influenza VirusImmunoglobulin GInfluenza VaccinesNeuraminidaseantibodyantigenic driftB cellsinfluenza

Identifiers

PMID39194245
PMCPMC11406888

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.