Evidence map›Paper›PMID 39194203›Full record

ArticleAntimicrobial agents and chemotherapy2024

IncC plasmid genome rearrangements influence the vertical and horizontal transmission tradeoff in

Margaux Allain, Thibaut Morel-Journel, Bénédicte Condamine, Benoist Gibeaux, Benoit Gachet, Rémi Gschwind, Erick Denamur, Luce Landraud

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Comparative Genomic Profiles ofMicroorganisms · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Margaux AllainUniversité Paris Cité and Université Sorbonne Paris Nord, INSERM, IAME, Paris, France.ORCID 0009-0001-8265-5224
Thibaut Morel-JournelUniversité Paris Cité and Université Sorbonne Paris Nord, INSERM, IAME, Paris, France.
Bénédicte CondamineUniversité Paris Cité and Université Sorbonne Paris Nord, INSERM, IAME, Paris, France.
Benoist GibeauxAP-HP, Laboratoire de Microbiologie Hygiène, Hôpital Louis Mourier, Colombes, France.
Benoit GachetUniversité Paris Cité and Université Sorbonne Paris Nord, INSERM, IAME, Paris, France.
Rémi GschwindUniversité Paris Cité and Université Sorbonne Paris Nord, INSERM, IAME, Paris, France.ORCID 0000-0001-7741-9764
Erick DenamurUniversité Paris Cité and Université Sorbonne Paris Nord, INSERM, IAME, Paris, France.ORCID 0000-0002-7860-1717
Luce LandraudUniversité Paris Cité and Université Sorbonne Paris Nord, INSERM, IAME, Paris, France.ORCID 0000-0001-8486-1403

Funding

Fondation pour la Recherche Médicale (FRM) DEQ20161136698
6 · The paper itself

Abstract

It has been shown that an evolutionary tradeoff between vertical (host growth rate) and horizontal (plasmid conjugation) transmissions contributes to global plasmid fitness. As conjugative IncC plasmids are important for the spread of multidrug resistance (MDR), in a broad range of bacterial hosts, we investigated vertical and horizontal transmissions of two multidrug-resistant IncC plasmids according to their backbones and MDR-region rearrangements, upon plasmid entry into a new host. We observed plasmid genome deletions after conjugation in three diverse natural

Indexed as

Conjugation, GeneticDrug Resistance, Multiple, BacterialEscherichia coliPlasmidsAnti-Bacterial AgentsEscherichia coli InfectionsGene Transfer, HorizontalGenome, BacterialAnti-Bacterial AgentsCTX-Mextended-spectrum beta-lactamasesfitness costIncC plasmidIS26tradeoff

Identifiers

PMID39194203
PMCPMC11459957

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.