Evidence map›Paper›PMID 39194034›Full record

ReviewBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica2024

The role and mechanisms of cordycepin in inhibiting cancer cells.

Gong Yu, Jiahua Peng, Lu Li, Wenbin Yu, Bin He, Bin Xie

Abstract readReview
In one paragraph

Review in Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Gels (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gong YuSchool of Chinese Medicine, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.ORCID http://orcid.org/0000-0002-1899-0976
Jiahua PengSchool of Chinese Medicine, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.ORCID http://orcid.org/0000-0002-8741-397X
Lu LiSchool of Chinese Medicine, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.ORCID http://orcid.org/0009-0007-2686-4121
Wenbin YuJiangxi Key Laboratory of Bioprocess Engineering, College of Life Sciences, Jiangxi Science & Technology Normal University, Nanchang, Jiangxi, China.ORCID http://orcid.org/0009-0009-3892-5643
Bin HeJiangxi Key Laboratory of Bioprocess Engineering, College of Life Sciences, Jiangxi Science & Technology Normal University, Nanchang, Jiangxi, China.ORCID http://orcid.org/0000-0003-1727-8132
Bin XieSchool of Chinese Medicine, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.ORCID http://orcid.org/0000-0003-2034-0160

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the escalating incidence and mortality rates of cancer, there is an ever-growing emphasis on the research of anticancer drugs. Cordycepin, the primary nucleoside antibiotic isolated from Cordyceps militaris, has emerged as a remarkable agent for cancer prevention and treatment. Functioning as a natural targeted antitumor drug, cordycepin assumes an increasingly pivotal role in cancer therapy. This review elucidates the mechanisms of cordycepin in inhibiting tumor cell proliferation, inducing apoptosis, as well as its capabilities in suppressing angiogenesis and metastasis. Moreover, the immunomodulatory effects of cordycepin in cancer treatment are explored. Additionally, the current status, challenges, and future prospects of cordycepin application in clinical trials are briefly discussed. The objective is to provide a valuable reference for the utilization of cordycepin in cancer treatment.

Indexed as

ApoptosisCell ProliferationDeoxyadenosinesNeoplasmsAntineoplastic AgentsHumansNeovascularization, PathologicAntineoplastic AgentscordycepinDeoxyadenosines

Identifiers

PMID39194034
PMCPMC11349152

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.