ArticleeLife2024
CCL28 modulates neutrophil responses during infection with mucosal pathogens.
Abstract read
In one paragraph
Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Tissue-Resident and Effector-Memory Lymphocyte Recruitment to the Ocular Mucosa Requires CCL28/CCR10 Signaling During Recurrent HSV-1 Infection.bioRxiv : the preprint server for biology · 2026Article
- Multi-omics elucidates the regulatory mechanisms of tryptophan in gut health of weaned piglets.Animal microbiome · 2026Article
- Uterine epithelial estrogen receptor α temporally regulates preimplantation uterine immunity involving interleukin-1β signaling.Reproductive and developmental medicine · 2026Article
- Immune dysregulation drives the relapse of peritoneal dialysis-associated peritonitis: a single-center prospective study.Frontiers in immunology · 2026Article
- Rules of engagement: Determinants of chemokine receptor activation and selectivity by CCL27 and CCL28.The Journal of biological chemistry · 2025Article
- Distinct Roles Between Eotaxin 1 and Eotaxin 2 in Asthmatic Airways.Clinical and translational allergy · 2025Article
- Article
- Transcriptome and proteome profile of jejunum in chickens challenged withFrontiers in microbiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors.
Gregory T Walker *Division of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, United States.ORCID https://orcid.org/0000-0002-3888-8143
Araceli Perez-Lopez *Division of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, United States.ORCID https://orcid.org/0000-0002-5399-1958
Steven SilvaDivision of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, United States.
Michael H LeeDivision of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, United States.
Elisabet BjånesDivision of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, United States.
Nicholas DillonDivision of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, United States.
Stephanie L BrandtDivision of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, United States.
Romana R GernerDivision of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, United States.
Karine MelchiorDivision of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, United States.
Grant J NortonDivision of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, United States.
Felix A ArguetaDivision of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, United States.
Frenchesca Dela PenaDivision of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, United States.
Lauren ParkDivision of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, United States.
Victor A Sosa-HernandezRed de Apoyo a la Investigación, Universidad Nacional Autónoma de México and Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, Mexico.
Rodrigo Cervantes-DiazRed de Apoyo a la Investigación, Universidad Nacional Autónoma de México and Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, Mexico.
Sandra Romero-RamirezRed de Apoyo a la Investigación, Universidad Nacional Autónoma de México and Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, Mexico.
Monica Cartelle GestalDepartment of Microbiology and Immunology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, United States.
Jose L Maravillas-MonteroRed de Apoyo a la Investigación, Universidad Nacional Autónoma de México and Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, Mexico.
Sean-Paul NuccioDivision of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, United States.ORCID https://orcid.org/0000-0002-9683-9278
Victor NizetDivision of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, United States.ORCID https://orcid.org/0000-0003-3847-0422
Manuela RaffatelluDivision of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, United States.ORCID https://orcid.org/0000-0001-6487-4215
Funding
San Diego Digestive Diseases Research CenterP30DK120515 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Tatiana Kisseleva · 2019 to 2026
$10.8MSystems Biology Approach to Redefine Susceptibility Testing and Treatment of MDR Pathogens in the Context of Host ImmunityU01AI124316 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PALSSON, BERNHARD O · 2016 to 2020
$10.2MRESEARCH IN INFECTIOUS DISEASEST32AI007036 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NIZET, VICTOR · 1985 to 2025
$9.2MTraining Grant in GastroenterologyT32DK007202 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GHOSH, PRADIPTA · 1985 to 2022
$7.7MMicrobiota Outgrowth by SalmonellaR01AI096528 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BAUMLER, ANDREAS J · 2011 to 2025
$6.1MC3-Dependent Intracellular Killing in Innate Immunity and Bacterial PathogenesisR01AI145325 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NIZET, VICTOR, RAFFATELLU, MANUELA · 2019 to 2023
$3.1MNutritional immunity during Salmonella infectionR01AI126277 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RAFFATELLU, MANUELA · 2016 to 2020
$1.9MNutritional immunity during Salmonella infectionR37AI126277 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Manuela Raffatellu · 2023 to 2026
$1.8MDeveloping Pediatric Clinical Pharmacologists for the Advancement of TherapeuticsT32HD087978 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NIZET, VICTOR, TREMOULET, ADRIANA H · 2016 to 2025
$1.5MAntimicrobial activity of Escherichia coli Nissle 1917 microcin MR21AI154644 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NOLAN, ELIZABETH M, RAFFATELLU, MANUELA · 2020 to 2021
$440kThe new chemokine CCL28 and its role during Salmonella infectionR21AI121928 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RAFFATELLU, MANUELA, ZLOTNIK, ALBERT · 2016 to 2017
$425kThe role of Salmonella protease PgtE in evading host immune responsesF32AI169989 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LEE, MICHAEL HWEEMOON · 2022 to 2023
$144kConsejo Nacional de Ciencia y Tecnología CONACyT- FOSISS A3-S-36875Consejo Nacional de Ciencia y Tecnología Grad School FellowshipCrohn's and Colitis Foundation 649744Eunice Kennedy Shriver National Institute of Child Health and Human Development HD087978Japan Agency for Medical Research and Development JP233fa627003Max Kade Foundation FellowshipNational Autonomous University of Mexico InnovaUNAM grantNational Institute of Allergy and Infectious Diseases AI007036National Institute of Allergy and Infectious Diseases AI121928National Institute of Allergy and Infectious Diseases AI124316National Institute of Allergy and Infectious Diseases AI145325National Institute of Allergy and Infectious Diseases AI169989National Institute of Allergy and Infectious Diseases Mucosal Immunology Studies TeamNIAID NIH HHS F32 AI169989NIAID NIH HHS R01 AI096528NIAID NIH HHS R01 AI126277NIAID NIH HHS R01 AI145325NIAID NIH HHS R21 AI121928NIAID NIH HHS R21 AI154644NIAID NIH HHS R37 AI126277NIAID NIH HHS T32 AI007036NIAID NIH HHS U01 AI124316NICHD NIH HHS T32 HD087978NIDDK NIH HHS DK007202NIDDK NIH HHS DK120515NIDDK NIH HHS P30 DK120515NIDDK NIH HHS T32 DK007202Public Health Service Grant AI145325São Paulo Research Foundation 2018/22042- 0São Paulo Research Foundation 2019/14833- 0Universidad Nacional Autónoma de México UNAM- DGAPA- PAPIIT Program grant IN213020University of California Alianza UCMX
Abstract
The chemokine CCL28 is highly expressed in mucosal tissues, but its role during infection is not well understood. Here, we show that CCL28 promotes neutrophil accumulation in the gut of mice infected with
Indexed as
Chemokines, CCNeutrophilsAcinetobacterAnimalsMiceMice, Inbred C57BLMice, KnockoutMucous MembraneReceptors, CCR3SalmonellaSalmonella InfectionsCcl28 protein, mouseChemokines, CCReceptors, CCR3Acinetobacterchemokinehumanimmunologyinfectious diseaseinflammationmicrobiologymousemucosaneutrophilSalmonella
Identifiers
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.