ArticleYonsei medical journal2024
Association between Low Serum Creatinine Levels and Knee Osteoarthritis in Koreans without Renal Insufficiency.
Article in Yonsei medical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Association between digestive diseases and symptomatic knee osteoarthritis in Chinese participants: a prospective cohort study.BMC public health · 2026Article
- Comparison of a patient-specific instrument and conventional high tibial Osteotomy: Accuracy of correction target and prevention of posterior tibial slope change.Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology · 2025Article
- Do Preparation Techniques Transform the Metabolite Profile of Platelet-Rich Plasma?Bioengineering (Basel, Switzerland) · 2025Article
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Authors and funding
3 authors.
Funding
Abstract
purposeThis study aimed to investigate the correlation between serum creatinine levels and the presence and severity of radiographic knee osteoarthritis (OA) in individuals aged ≥50 years while adjusting for potential confounders. MATERIALS AND
methodsCross-sectional data from the 2009-2011 Korea National Health and Nutrition Examination Survey comprising 3428 individuals aged ≥50 years were utilized. The Kellgren-Lawrence (K-L) grading scale was used to assess the radiographic presence and severity of knee OA. Logistic regression and receiver operating characteristic analyses were used to investigate the association between serum creatinine levels and the presence of knee OA, whereas ordinal regression was used to assess the impact of creatinine levels on knee OA severity.
resultsThe presence of radiographic knee OA conferred by low serum creatinine levels was found to be significant in both sexes [odds ratio (OR), 0.118; 95% confidence interval (CI), 0.045-0.314,
conclusionLow serum creatinine level was associated with a higher presence of knee OA in both men and women, and was also linked to the severity of the disease. These findings suggest that the serum creatinine level may be a potential biomarker for assessing the presence and severity of knee OA.
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