Evidence map›Paper›PMID 39193480›Full record

ArticleOxford medical case reports2024

Melatonin-induced symptomatic bradycardia in an otherwise healthy male: a case report.

Asim Alawad, Wala Sati, Sara M I Ahmed, Moayed Elgassim, Mohamad Elgassim, Abderahman Balal

Abstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Asim AlawadEmergency Medicine Department, Hamad General Hospital, P.O. Box: 3050, Doha, Qatar.ORCID https://orcid.org/0009-0003-7780-7611
Wala SatiEmergency Medicine Department, Hamad General Hospital, P.O. Box: 3050, Doha, Qatar.ORCID https://orcid.org/0009-0009-1574-9034
Sara M I AhmedEmergency Medicine Department, Hamad General Hospital, P.O. Box: 3050, Doha, Qatar.ORCID https://orcid.org/0000-0003-4499-5006
Moayed ElgassimEmergency Medicine Department, Hamad General Hospital, P.O. Box: 3050, Doha, Qatar.ORCID https://orcid.org/0000-0003-2836-0334
Mohamad ElgassimEmergency Medicine Department, Hamad General Hospital, P.O. Box: 3050, Doha, Qatar.ORCID https://orcid.org/0000-0002-6556-964X
Abderahman BalalEmergency Medicine Department, Hamad General Hospital, P.O. Box: 3050, Doha, Qatar.ORCID https://orcid.org/0009-0008-1170-3648

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melatonin, a pineal gland hormone closely associated with the circadian rhythm, has been trending over the past years as an over-the-counter medication to aid with sleep disturbances. Although generally believed to be safe, recent studies show negative inotropic and chronotropic effects on the heart rate and blood pressure in humans. Several studies suggested that melatonin induces cardiac vagal tone and affects heart rate and mean arterial pressure. Limited literature is currently available on the effects of melatonin beyond its sleep function. We present a case of a healthy 22-year-old male who visited the emergency department reporting palpitations and dizziness following the ingestion of 20 mg of melatonin. Subsequent examinations revealed marked bradycardia. Fortunately, the patient experienced spontaneous resolution of the bradycardia without necessitating intervention after a few hours of observation, and he was observed and discharged.

Indexed as

bradycardiamelatoninmelatonin side-effect

Identifiers

PMID39193480
PMCPMC11348002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.