Evidence map›Paper›PMID 39193465›Full record

ReviewDementia & neuropsychologia2024

Quality of life in persons with mild cognitive impairment: a systematic review and meta-analysis.

Priya Gopalakrishnan, Shivani Tiwari, Ravishankar Nagaraja, Gopee Krishnan

Abstract readReview
In one paragraph

Review in Dementia & neuropsychologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  7. The indirect effects of cognitive function in the association between stroke and quality of life among older adults in a rural community: A cross-sectional study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Priya GopalakrishnanManipal Academy of Higher Education, Manipal College of Health Professions, Department of Speech and Hearing, Manipal, Karnataka, India.ORCID https://orcid.org/0009-0002-0529-2041
Shivani TiwariManipal Academy of Higher Education, Manipal College of Health Professions, Department of Speech and Hearing, Manipal, Karnataka, India.ORCID https://orcid.org/0000-0002-4345-5000
Ravishankar NagarajaUniversity of Delhi, Vallabhbhai Patel Chest Institute, Department of Biostatistics, Delhi, India.ORCID https://orcid.org/0000-0002-9533-039X
Gopee KrishnanManipal Academy of Higher Education, Manipal College of Health Professions, Department of Speech and Hearing, Manipal, Karnataka, India.ORCID https://orcid.org/0000-0001-9509-5900

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global increase in the aging population has raised concerns over various age-related conditions like dementia and mild cognitive impairment (MCI) and their consequences on the affected persons. People with MCI exhibit cognitive deficits more significantly than expected for their age and literacy level. Though the nature of this condition is considered "mild", studies have reported that even more subtle deficits can influence the quality of life (QOL). Objective: The present work aimed at exploring and comparing QOL in older adults with and without MCI through a systematic review and meta-analysis. Methods: After a detailed search of articles till May 2021 in the relevant electronic databases (PubMed Central, PubMed, Scopus, CINAHL Plus, Web of Science, ProQuest, and Cochrane) using the keywords "mild cognitive impairment", "quality of life", "old", "old aged", "aged", "older adult", "geriatrics", "healthy controls", "healthy participants", and "normal controls", we included 23 articles in the systematic review and 12 in the meta-analysis. Results: The quality of all the included articles were assessed using the Modified Downs and Black tool. Most of the studies in the systematic review demonstrated differences in QOL scores in older adults with MCI compared to healthy older adults. However, meta-analysis findings suggest that older adults with MCI had statistically non-significant yet lower differences in QOL compared to their healthy counterparts. Conclusion: Future research should focus on developing QOL assessment tools specifically for older adults with MCI and follow-up studies that could provide better knowledge of their changing cognitive profile and life quality.

Indexed as

AgedCognitive DysfunctionMeta-analysisQuality of LifeSystematic Review

Identifiers

PMID39193465
PMCPMC11348882

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.