Evidence map›Paper›PMID 39193420›Full record

ArticleClinical mass spectrometry (Del Mar, Calif.)2016

Rapid screening and identification of novel psychoactive substances using PaperSpray interfaced to high resolution mass spectrometry.

Joseph Kennedy, Kevin G Shanks, Kristine Van Natta, Maria C Prieto Conaway, Justin M Wiseman, Brian Laughlin, Marta Kozak

Abstract read
In one paragraph

Article in Clinical mass spectrometry (Del Mar, Calif.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joseph KennedyProsolia Inc., Indianapolis, IN, United States.
Kevin G ShanksAIT Laboratories, Indianapolis, IN, United States.
Kristine Van NattaThermo Fisher Scientific, San Jose, CA, United States.
Maria C Prieto ConawayThermo Fisher Scientific, San Jose, CA, United States.
Justin M WisemanProsolia Inc., Indianapolis, IN, United States.
Brian LaughlinProsolia Inc., Indianapolis, IN, United States.
Marta KozakThermo Fisher Scientific, San Jose, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The simple and rapid detection and identification of designer drugs is of substantial importance to forensic scientists and law enforcement. Although synthetic cathinones, cannabinoids, and other common novel psychoactive substances (NPS) are produced for purposes that do not include human consumption, they are regularly abused. The analysis of these compounds is often achieved using mass spectrometry, but can be complicated by the lack of spectral libraries and the scarcity of simple and reliable sample introduction techniques. PaperSpray® ionization is a new, automated technique for rapid analysis of samples, without chromatography or prior purification. Matrix, such as powder or plant material, is dissolved or extracted with common solvents and deposited directly on disposable PaperSpray® cartridges for high-throughput, automated analysis. The combination of PaperSpray® sample introduction and High Resolution Accurate Mass Spectrometry (HRAM) provides a powerful and simple tool for identification of new substances, without requiring reference standards.

Indexed as

Novel psychoactive substancesPaperSpray ionizationSynthetic cannabinoids

Identifiers

PMID39193420
PMCPMC11322720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.