Evidence map›Paper›PMID 39193154›Full record

ArticleWorld journal of clinical oncology2024

Prognostic value and predictive model of tumor markers in stage I to III gastric cancer patients.

Ai-Hua Sun, Xin-Yu Zhang, Yang-Yang Huang, Lei Chen, Qing Wang, Xiao-Cong Jiang

Abstract read
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Article in World journal of clinical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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3 citing papers in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Ai-Hua SunDepartment of Radiotherapy Oncology, Huizhou Municipal Central Hospital, Huizhou 516001, Guangdong Province, China.
Xin-Yu ZhangDepartment of Radiotherapy Oncology, Huizhou Municipal Central Hospital, Huizhou 516001, Guangdong Province, China.
Yang-Yang HuangDepartment of Hepatobiliary Surgery, Fujian Provincial Hospital, Fuzhou 350001, China.
Lei ChenDepartment of General Surgery, Xiang'an Hospital of Xiamen University, Xiamen 361102, Fujian Province, China.
Qing WangDepartment of General Surgery, Xiang'an Hospital of Xiamen University, Xiamen 361102, Fujian Province, China.
Xiao-Cong JiangDepartment of Radiotherapy Oncology, Huizhou Municipal Central Hospital, Huizhou 516001, Guangdong Province, China. onion1021@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreoperative serum tumor markers have been widely used in the diagnosis and treatment of gastric cancer patients. However, few studies have evaluated the prognosis of gastric cancer patients by establishing statistical models with multiple serum tumor indicators.

aimTo explore the prognostic value and predictive model of tumor markers in stage I and III gastric cancer patients.

methodsFrom October 2018 to April 2020, a total of 1236 patients with stage I to III gastric cancer after surgery were included in our study. The relationship between serum tumor markers and clinical and pathological data were analyzed. We established a statistical model to predict the prognosis of gastric cancer based on the results of COX regression analysis. Overall survival (OS) was also compared across different stages of gastric cancer.

resultsThe deadline for follow-up was May 31, 2023. A total of 1236 patients were included in our study. Univariate analysis found that age, clinical stage, T and N stage, tumor location, differentiation, Borrmann type, size, and four serum tumor markers were prognostic factors of OS (

conclusionOur statistical model can effectively predict the prognosis of gastric cancer patients.

Indexed as

Gastric cancerModelOverall survivalPrognosisTumor marker

Identifiers

PMID39193154
PMCPMC11346068

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