ArticleClinical mass spectrometry (Del Mar, Calif.)2016
A proposal to improve calibration and outlier detection in high-throughput mass spectrometry.
Article in Clinical mass spectrometry (Del Mar, Calif.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Calibration Practices in Clinical Mass Spectrometry: Review and Recommendations.Annals of laboratory medicine · 2023Pooled it
- Quantitative sampling by IR-MALDESI is not susceptible to tissue heterogeneity in a multi-organ model.Analytical and bioanalytical chemistry · 2025Article
- Green Synthesis, Characterization, Antimicrobial, Anti-Cancer, and Optimization of Colorimetric Sensing of Hydrogen Peroxide of Algae Extract Capped Silver Nanoparticles.Nanomaterials (Basel, Switzerland) · 2020Article
- Considerations for MALDI-Based Quantitative Mass Spectrometry Imaging Studies.Journal of proteome research · 2020Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Instrument calibration, required for any accurate quantitative calculation, is a trivial process when performed correctly, but is also full of easily overlooked stumbling blocks. To minimize the risk of error associated with improper calibrations, national and international guidance dictates a minimum number of calibrators and the threshold at which a measurement becomes an outlier. Evidence from industry practice, which conflicts with regulatory guidance, suggests that most groups are focused on remapping their detector with each run. We present a
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.