Evidence map›Paper›PMID 39192727›Full record

ArticleJournal of the Royal Society, Interface2024

AT1b receptors contribute to regional disparities in angiotensin II mediated aortic remodelling in mice.

Cristina Cavinato, Bart Spronck, Alexander W Caulk, Sae-Il Murtada, Jay D Humphrey

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Royal Society, Interface, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cristina CavinatoDepartment of Biomedical Engineering, Yale University , New Haven, CT, USA.ORCID 0000-0002-6021-8920
Bart SpronckDepartment of Biomedical Engineering, Yale University , New Haven, CT, USA.ORCID 0000-0003-1076-1922
Alexander W CaulkDepartment of Biomedical Engineering, Yale University , New Haven, CT, USA.
Sae-Il MurtadaDepartment of Biomedical Engineering, Yale University , New Haven, CT, USA.
Jay D HumphreyDepartment of Biomedical Engineering, Yale University , New Haven, CT, USA.ORCID 0000-0003-1011-2025

Funding

Agence Nationale de la RechercheHORIZON EUROPE European Innovation CouncilNederlandse Organisatie voor Wetenschappelijk OnderzoekNIH HHS
6 · The paper itself

Abstract

The renin-angiotensin system plays a key role in regulating blood pressure, which has motivated many investigations of associated mouse models of hypertensive arterial remodelling. Such studies typically focus on histological and cell biological changes, not wall mechanics. This study explores tissue-level ramifications of chronic angiotensin II infusion in wild-type (WT) and type 1b angiotensin II (AngII) receptor null (

Indexed as

Angiotensin IIMice, KnockoutReceptor, Angiotensin, Type 1Vascular RemodelingAnimalsAorta, ThoracicFemaleMaleMiceAngiotensin IIReceptor, Angiotensin, Type 1aortahypertensioninflammationremodellingsexstiffness

Identifiers

PMID39192727
PMCPMC11350382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.