Evidence map›Paper›PMID 39192377›Full record

ArticleEuropean journal of medical research2024

A

Weijun Liu, Qingbo Li, Weizhi Fang, Lei Cai, Zhengkun Wang, Bowen Kou, Chuankun Zhou, Yichi Zhou, Zhi Yao, Mengcheng Wei and 1 more

Abstract read
In one paragraph

Article in European journal of medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Involvement of Adenosine ABrain and behavior · 2026
    Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Weijun LiuDepartment of Spine Surgery, Wuhan Fourth Hospital, Hanzheng Street, 473#, QiaoKou District, Wuhan, 430033, China. wuhanspine@163.com.
Qingbo LiDepartment of Spine Surgery, Wuhan Fourth Hospital, Hanzheng Street, 473#, QiaoKou District, Wuhan, 430033, China.
Weizhi FangDepartment of Spine Surgery, Wuhan Fourth Hospital, Hanzheng Street, 473#, QiaoKou District, Wuhan, 430033, China.
Lei CaiDepartment of Spine Surgery, Wuhan Fourth Hospital, Hanzheng Street, 473#, QiaoKou District, Wuhan, 430033, China.
Zhengkun WangDepartment of Spine Surgery, Wuhan Fourth Hospital, Hanzheng Street, 473#, QiaoKou District, Wuhan, 430033, China.
Bowen KouDepartment of Spine Surgery, Wuhan Fourth Hospital, Hanzheng Street, 473#, QiaoKou District, Wuhan, 430033, China.
Chuankun ZhouDepartment of Spine Surgery, Wuhan Fourth Hospital, Hanzheng Street, 473#, QiaoKou District, Wuhan, 430033, China.
Yichi ZhouDepartment of Spine Surgery, Wuhan Fourth Hospital, Hanzheng Street, 473#, QiaoKou District, Wuhan, 430033, China.
Zhi YaoDepartment of Spine Surgery, Wuhan Fourth Hospital, Hanzheng Street, 473#, QiaoKou District, Wuhan, 430033, China.
Mengcheng WeiDepartment of Spine Surgery, Wuhan Fourth Hospital, Hanzheng Street, 473#, QiaoKou District, Wuhan, 430033, China.
Shishuang ZhangDepartment of Spine Surgery, Wuhan Fourth Hospital, Hanzheng Street, 473#, QiaoKou District, Wuhan, 430033, China.

Funding

Natrual S 2021CFB522
6 · The paper itself

Abstract

backgroundReduction of inflammatory damage and inhibition of nucleus pulposus (NP) apoptosis are considered to be the main effective therapy idea to reverse the intervertebral disc degeneration (IDD) and alleviate the chronic low back pain. The adenosine A2A receptor (A2AR), as a member of G protein-coupled receptor families, plays an important role in the anti-inflammation and relieving pain. So far, the impact of A2AR on IDD therapy is unclear. The aim of this study was to explore the role of Adenosine A MATERIALS AND

methodsIL-1β and acupuncture was used to establish IDD model rats. A

resultsA

conclusionsThe activation of A

Indexed as

Cyclic AMP-Dependent Protein KinasesInflammationIntervertebral Disc DegenerationNF-kappa BReceptor, Adenosine A2ASignal TransductionAdenosineAdenosine A2 Receptor AgonistsAnimalsCyclic AMPDisease Models, AnimalMaleNucleus PulposusPhenethylaminesRatsRats, Sprague-Dawley2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosineAdenosineAdenosine A2 Receptor AgonistsCyclic AMPCyclic AMP-Dependent Protein KinasesNF-kappa BPhenethylaminesReceptor, Adenosine A2AA2ARCAMP/PKAInflammatory damageIntervertebral disc degenerationNF-κB signaling pathwayNucleus pulposus

Identifiers

PMID39192377
PMCPMC11348769

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.