Evidence map›Paper›PMID 39192130›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

Epidemiological Study in Antiviral Innate Immunity.

Xiaoyu Zhao, Yuting Liu, Ruogu Cheng, Chunfu Zheng, Pei Shang

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaoyu ZhaoDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong Province, China.
Yuting LiuDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong Province, China.
Ruogu ChengDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong Province, China.
Chunfu ZhengDepartment of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, AB, Canada.
Pei ShangDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong Province, China. Shang.Pei@Mayo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This chapter summarizes the epidemiological study design of natural immune epidemiology studies based on recent COVID-19-related research. The epidemiological studies on antiviral innate immunity have mainly included randomized controlled trials (RCTs) and observational studies. Importantly, this chapter will discuss how to use these methodologies to answer an epidemiological question of natural immunity in the viral infection process based on previous studies. An observational case- or cohort-based study of antiviral innate immunity may support this theoretical hypothesis but is not appropriate for clinical practice or treatment. RCTs are the gold standard for epidemiological studies and occupy a greater role in the hierarchy of evidence.

Indexed as

COVID-19Immunity, InnateSARS-CoV-2Antiviral AgentsEpidemiologic StudiesHumansObservational Studies as TopicRandomized Controlled Trials as TopicAntiviral AgentsAntiviral innate immunityCOVID-19Epidemiological studyObservational studyRandomized controlled trial

Identifiers

PMID39192130

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.