Evidence map›Paper›PMID 39192088›Full record

ReviewAbdominal radiology (New York)2025

Discontinuous peripheral enhancement of focal liver lesions on CT and MRI: outside the box of typical cavernous hemangioma.

Francesco Matteini, Roberto Cannella, Marco Dioguardi Burgio, Chiara Torrisi, Riccardo Sartoris, Giuseppe Brancatelli, Valérie Vilgrain, Maxime Ronot, Federica Vernuccio

Abstract readReview
In one paragraph

Review in Abdominal radiology (New York), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Diagnosis and Management of Benign Liver Tumors.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Francesco MatteiniDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University Hospital of Palermo, Via del Vespro 129, 90127, Palermo, Italy. dott.francescomatteini@gmail.com.ORCID 0000-0002-6166-9942
Roberto CannellaDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University Hospital of Palermo, Via del Vespro 129, 90127, Palermo, Italy.
Marco Dioguardi BurgioDepartment of Radiology, Hôpital Beaujon, AP-HP.Nord, Paris, France.
Chiara TorrisiIRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089, Milan, Italy.
Riccardo SartorisDepartment of Radiology, Hôpital Beaujon, AP-HP.Nord, Paris, France.
Giuseppe BrancatelliDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University Hospital of Palermo, Via del Vespro 129, 90127, Palermo, Italy.
Valérie VilgrainDepartment of Radiology, Hôpital Beaujon, AP-HP.Nord, Paris, France.
Maxime RonotDepartment of Radiology, Hôpital Beaujon, AP-HP.Nord, Paris, France.
Federica VernuccioDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University Hospital of Palermo, Via del Vespro 129, 90127, Palermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The discontinuous peripheral enhancement is a pattern of enhancement usually attributed to typical cavernous hemangioma, that is the most common benign solid lesion of the liver. The discontinuous peripheral enhancement, however, may be encountered in many other benign and malignant focal liver lesions as an atypical presentation or evolution, and hemangiomas with discontinuous peripheral hyperenhancement on hepatic arterial phase may not always have the typical post-contrast pattern on portal venous and delayed phases. Therefore, abdominal radiologists may be challenged in their practice by lesions with discontinuous peripheral enhancement. This pictorial essay aims to review the spectrum of benign and malignant focal liver lesions that may show discontinuous peripheral enhancement. A particular point of interest is the diagnostic tree pathway that may guide the radiologists in the differential diagnosis.

Indexed as

Hemangioma, CavernousLiver NeoplasmsMagnetic Resonance ImagingTomography, X-Ray ComputedContrast MediaDiagnosis, DifferentialHumansLiverContrast MediaContrast agent intravenousCTHaemangiomaHepatic infectionHepatocellular carcinomaLiver imagingLiver metastasesLiver neoplasmMagnetic resonance imaging

Identifiers

PMID39192088
PMCPMC11794645

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.