Evidence map›Paper›PMID 39192030›Full record

ReviewJournal of neurology2024

Akinetic crisis and withdrawal syndromes: guideline "Parkinson's disease" of the German Society of Neurology.

Monika Pötter-Nerger, Matthias Löhle, Günter Höglinger, German Parkinson‘s Guideline Group

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Monika Pötter-NergerDepartment of Neurology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany. m.poetter-nerger@uke.de.ORCID http://orcid.org/0000-0001-7680-2147
Matthias LöhleDepartment of Neurology, University Medicine Rostock, Rostock, Germany.
Günter HöglingerDepartment of Neurology, LMU University Hospital, Ludwig-Maximilians-Universität (LMU) München, Munich, Germany.
German Parkinson‘s Guideline Group

Funding

Deutsche Forschungsgemeinschaft SFB 936-C8
6 · The paper itself

Abstract

The akinetic crisis is a well-known, rare, potentially life-threatening condition in Parkinson's disease with subacute worsening of akinesia, rigidity, fever, impaired consciousness, accompanying vegetative symptoms and transient dopa-resistance. The akinetic crisis was historically supposed to be a "withdrawal syndrome" in the sense of discontinuation of dopaminergic medication. Recently, other "withdrawal syndromes" as the specific "dopamine agonist withdrawal syndrome" or "deep brain stimulation withdrawal syndrome" have been described as emergency situations with specific subacute symptom constellations. All three conditions require immediate start of the adequate therapy to improve the prognosis. Here, the diagnostic criteria and treatment options of these three acute, severely disabling syndromes will be reported along the current guidelines of the German Parkinson Guideline Group.

Indexed as

Parkinson DiseaseSubstance Withdrawal SyndromeAntiparkinson AgentsDeep Brain StimulationGermanyHumansNeurologyPractice Guidelines as TopicSocieties, MedicalAntiparkinson AgentsAkinetic crisisDeep brain stimulation withdrawal syndromeDiagnostic criteriaDopamine agonist withdrawal syndromeGerman Parkinson GuidelineTherapy

Identifiers

PMID39192030
PMCPMC11447035

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.