Evidence map›Paper›PMID 39191926›Full record

Trial reportInternational journal of obesity (2005)2025

Randomized non-inferiority trial comparing an asynchronous remotely-delivered versus clinic-delivered lifestyle intervention.

Sherry L Pagoto, Jared M Goetz, Ran Xu, Monica L Wang, Lindsay Palmer, Stephenie C Lemon

Registry-linked trialAbstract readComparative StudyEquivalence TrialRandomized Controlled Trial
In one paragraph

Trial report in International journal of obesity (2005), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02646618 (Get Social), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02646618 nacompletednot on this map

Get Social: Randomized Trial of a Social Network Delivered Lifestyle Intervention

TypeinterventionalSponsorUniversity of ConnecticutRan2016 to 2020Enrolled329ConditionsWeight LossArmsGet Social, Traditional, Smartphone
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sherry L PagotoDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT, USA. sherry.pagoto@uconn.edu.ORCID 0000-0002-2462-8797
Jared M GoetzDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT, USA.
Ran XuDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT, USA.
Monica L WangBoston University School of Public Health, Boston, MA, USA.
Lindsay PalmerUniversity of Massachusetts Chan Medical School, Department of Population and Quantitative Health Sciences, Worcester, MA, USA.ORCID 0000-0002-5415-9186
Stephenie C LemonUniversity of Massachusetts Chan Medical School, Department of Population and Quantitative Health Sciences, Worcester, MA, USA.

Funding

Get Social: Randomized Trial of a Social Network Delivered Lifestyle InterventionR01DK103944 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI PAGOTO, SHERRY L. · 2015 to 2018
$2.0M
A non-inferiority trial comparing synchronous and asynchronous remotely-delivered lifestyle interventionsR01DK136795 · NIDDK · UNIVERSITY OF CONNECTICUT STORRS · PI SHERRY L. PAGOTO · 2023 to 2026
$1.7M
Mentoring in mHealth and Social Networking Interventions for CVD Risk ReductionK24HL124366 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI PAGOTO, SHERRY L. · 2015 to 2024
$1.1M
NHLBI NIH HHS K24 HL124366NIDDK NIH HHS R01 DK103944NIDDK NIH HHS R01 DK136795
6 · The paper itself

Abstract

objectiveLifestyle interventions are effective, but those delivered via in-person group meetings have poor scalability and reach. Research is needed to establish if remotely delivered lifestyle interventions are non-inferior to in-person delivered lifestyle interventions.

methodsWe conducted a randomized non-inferiority trial (N = 329) to compare a lifestyle intervention delivered remotely and asynchronously via an online social network (Get Social condition) to one delivered via in-person groups (Traditional condition). We hypothesized that the Get Social condition would result in a mean percent weight loss at 12 months that was not inferior to the Traditional condition. Additional outcomes included intervention delivery costs per pound lost and acceptability (e.g., convenience, support, modality preferences).

resultsAt 12 months, no significant difference in percent weight change was observed between the Get Social and Traditional conditions (2.7% vs. 3.7%, p = 0.17) however, criteria for non-inferiority were not met. The Get Social condition costs $21.45 per pound lost versus $26.24 for the Traditional condition. A greater percentage of Get Social condition participants rated participation as convenient (65% vs 44%; p = 0.001).

conclusionsResults revealed a remotely-delivered asynchronous lifestyle intervention resulted in slightly less weight loss than an in-person version but may be more economical and convenient.

trial registrationClinicalTrials.gov NCT02646618; https://clinicaltrials.gov/ct2/show/NCT02646618 .

Indexed as

Weight LossAdultFemaleHumansLife StyleMaleMiddle AgedObesityWeight Reduction Programs

Identifiers

PMID39191926
PMCPMC12226821

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.