Evidence map›Paper›PMID 39191912›Full record

ArticleScientific reports2024

Development and validation of a new scoring system to discriminate between uncomplicated and complicated appendicitis.

Mikito Mori, Kiyohiko Shuto, Chihiro Kosugi, Kazuo Narushima, Atsushi Hirano, Akihiro Usui, Hiroyuki Nojima, Mihono Hirota, Tetsutaro Sazuka, Masato Yamazaki and 4 more

Abstract readValidation Study
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Association of Sex, Age, and Inflammatory Cell Counts with Complicated Acute Appendicitis.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mikito MoriDepartment of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, Ichihara, 299-0111, Japan. mikimori45@yahoo.co.jp.ORCID 0000-0001-8946-3471
Kiyohiko ShutoDepartment of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, Ichihara, 299-0111, Japan.
Chihiro KosugiDepartment of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, Ichihara, 299-0111, Japan.
Kazuo NarushimaDepartment of Esophago-Gastrointestinal Surgery, Chiba Cancer Center, Chiba, Japan.
Atsushi HiranoDepartment of Surgery, Secomedic Hospital, Funabashi, Japan.
Akihiro UsuiDepartment of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, Ichihara, 299-0111, Japan.
Hiroyuki NojimaDepartment of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, Ichihara, 299-0111, Japan.
Mihono HirotaDepartment of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, Ichihara, 299-0111, Japan.
Tetsutaro SazukaDepartment of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, Ichihara, 299-0111, Japan.
Masato YamazakiDepartment of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, Ichihara, 299-0111, Japan.
Takashi FujinoDepartment of Pathology, Teikyo University Chiba Medical Center, Ichihara, Japan.
Kazuto YamazakiDepartment of Pathology, Teikyo University Chiba Medical Center, Ichihara, Japan.
Hiroaki ShimizuDepartment of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, Ichihara, 299-0111, Japan.
Keiji KodaDepartment of Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, Ichihara, 299-0111, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A scoring system to discriminate between uncomplicated and complicated appendicitis is beneficial to determine the optimal treatment for acute appendicitis. We developed a scoring system to discriminate between uncomplicated and complicated appendicitis and assessed the clinical usefulness of the scoring system using external validation. A total of 299 patients with acute appendicitis were retrospectively reviewed. One hundred and ninety-nine patients were assigned to the model development group, while the other 100 patients were assigned to an external validation group. A scoring system for complicated appendicitis was created using a final multivariate logistic regression model with six independent predictors. The area under the receiver operating characteristic curve of the scoring system was 0.882 (95% confidence interval: 0.835-0.929). The cutoff point of the scoring system was 12, and the sensitivity and specificity were 82.9% and 86.2%, respectively. In the external validation group, the area under the receiver operating characteristic curve of the scoring system was 0.868 (95% confidence interval 0.794-0.942), and there was no significant difference between the groups in the area under the receiver operating characteristic curve (P = 0.750). Our newly developed scoring system may contribute to prompt determination of the optimal treatment for acute appendicitis.

Indexed as

AppendicitisROC CurveAcute DiseaseAdolescentAdultAgedAppendectomyFemaleHumansLogistic ModelsMaleMiddle AgedRetrospective StudiesSensitivity and SpecificityYoung AdultAcute appendicitisComplicated appendicitisExternal validationLogistic regression modelUncomplicated appendicitis

Identifiers

PMID39191912
PMCPMC11349979

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.