Evidence map›Paper›PMID 39191753›Full record

ArticleNature communications2024

Enantiospecificity in NMR enabled by chirality-induced spin selectivity.

T Georgiou, J L Palma, V Mujica, S Varela, M Galante, V J Santamaría-García, L Mboning, R N Schwartz, G Cuniberti, L-S Bouchard

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

T GeorgiouMolecular Biology Interdepartmental Program (MBIDP), The Molecular Biology Institute, University of California Los Angeles, 611 Charles E. Young Drive East, Los Angeles, CA, 90095-1570, USA.
J L PalmaDepartment of Chemistry, Penn State University, 2201 University Drive, Lemont Furnace, PA, 15456, USA.ORCID http://orcid.org/0000-0002-2611-7560
V MujicaSchool of Molecular Sciences, Arizona State University, 551 E University Dr, Tempe, AZ, 85281, USA.ORCID http://orcid.org/0000-0002-5237-4851
S VarelaInstitute for Materials Science and Max Bergmann Center of Biomaterials, TU Dresden, 01062, Dresden, Germany.ORCID http://orcid.org/0000-0002-9608-0601
M GalanteSchool of Molecular Sciences, Arizona State University, 551 E University Dr, Tempe, AZ, 85281, USA.
V J Santamaría-GarcíaDepartment of Mechanical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts, 02139, US.ORCID http://orcid.org/0000-0001-9284-1218
L MboningDepartment of Chemistry and Biochemistry, University of California Los Angeles, 607 Charles E. Young Dr. East, Los Angeles, CA, 90095-1569, USA.
R N SchwartzDepartment of Electrical and Computer Engineering, University of California Los Angeles, 420 Westwood Plaza, Los Angeles, CA, 90095-1594, USA.
G CunibertiInstitute for Materials Science and Max Bergmann Center of Biomaterials, TU Dresden, 01062, Dresden, Germany. gianaurelio.cuniberti@tu-dresden.de.ORCID http://orcid.org/0000-0002-6574-7848
L-S BouchardMolecular Biology Interdepartmental Program (MBIDP), The Molecular Biology Institute, University of California Los Angeles, 611 Charles E. Young Drive East, Los Angeles, CA, 90095-1570, USA. bouchard@chem.ucla.edu.ORCID http://orcid.org/0000-0003-4151-5628

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spin polarization in chiral molecules is a magnetic molecular response associated with electron transport and enantioselective bond polarization that occurs even in the absence of an external magnetic field. An unexpected finding by Santos and co-workers reported enantiospecific NMR responses in solid-state cross-polarization (CP) experiments, suggesting a possible additional contribution to the indirect nuclear spin-spin coupling in chiral molecules induced by bond polarization in the presence of spin-orbit coupling. Herein we provide a theoretical treatment for this phenomenon, presenting an effective spin-Hamiltonian for helical molecules like DNA and density functional theory (DFT) results on amino acids that confirm the dependence of J-couplings on the choice of enantiomer. The connection between nuclear spin dynamics and chirality could offer insights for molecular sensing and quantum information sciences. These results establish NMR as a potential tool for chiral discrimination without external agents.

Identifiers

PMID39191753
PMCPMC11349874

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.