Evidence map›Paper›PMID 39190927›Full record

SynthesisDiabetes care2024

Effectiveness of Multilevel and Multidomain Interventions to Improve Glycemic Control in U.S. Racial and Ethnic Minority Populations: A Systematic Review and Meta-analysis.

Eli M Falk, Erin M Staab, Amber N Deckard, Sofia I Uranga, Nikita C Thomas, Wen Wan, Andrew J Karter, Elbert S Huang, Monica E Peek, Neda Laiteerapong

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Diabetes care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Effects of Multilevel and Multidomain Interventions on Glycemic Control in U.S. Hispanic Populations.International journal of environmental research and public health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eli M FalkUniversity of Chicago Biological Sciences Division, University of Chicago, Chicago, IL.
Erin M StaabUniversity of Chicago Biological Sciences Division, University of Chicago, Chicago, IL.
Amber N DeckardUniversity of Chicago Biological Sciences Division, University of Chicago, Chicago, IL.
Sofia I UrangaUniversity of Chicago Biological Sciences Division, University of Chicago, Chicago, IL.
Nikita C ThomasUniversity of Chicago Biological Sciences Division, University of Chicago, Chicago, IL.
Wen WanUniversity of Chicago Biological Sciences Division, University of Chicago, Chicago, IL.ORCID 0000-0002-7464-6563
Andrew J KarterKaiser Permanente Division of Research, Pleasanton, CA.ORCID 0000-0001-5527-316X
Elbert S HuangUniversity of Chicago Biological Sciences Division, University of Chicago, Chicago, IL.ORCID 0000-0002-4628-2061
Monica E PeekUniversity of Chicago Biological Sciences Division, University of Chicago, Chicago, IL.
Neda LaiteerapongUniversity of Chicago Biological Sciences Division, University of Chicago, Chicago, IL.ORCID 0000-0003-0124-4325

Funding

Voice-Activated Technology to Improve Mobility & Reduce Health Disparities: EngAGEing African American Older Adult-Care Partner DyadsP50MD017349 · NIMHD · UNIVERSITY OF CHICAGO · PI BAIG, ARSHIYA AHMED · 2021 to 2025
$24.3M
Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI MILDA Renne SAUNDERS · 2011 to 2026
$10.0M
Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
Predicting and Reducing Future Health Disparities for U.S. Adults with DiabetesR01MD013420 · NIMHD · UNIVERSITY OF CHICAGO · PI LAITEERAPONG, NEDA · 2018 to 2021
$1.6M
Research and Mentorship in Medical Decision Making for Chronic Diseases of Older AdultsK24AG069080 · NIA · UNIVERSITY OF CHICAGO · PI HUANG, ELBERT S. · 2020 to 2024
$583k
Division of Diabetes, Endocrinology, and Metabolic Diseases 2P30DK092949NIA NIH HHS K24 AG069080NIA NIH HHS K24AG069080NIDDK NIH HHS P30 DK092924NIDDK NIH HHS P30 DK092949NIMHD NIH HHS P50 MD017349NIMHD NIH HHS P50MD017349NIMHD NIH HHS R01 MD013420
6 · The paper itself

Abstract

backgroundRacial and ethnic disparities in type 2 diabetes outcomes are a major public health concern. Interventions targeting multiple barriers may help address disparities. PURPOSE: To conduct a systematic review and meta-analysis of diabetes self-management education (DSME) interventions in minority populations. We hypothesized that interventions addressing multiple levels (individual, interpersonal, community, and societal) and/or domains (biological, behavioral, physical/built environment, sociocultural environment, and health care system) would have the greatest effect on hyperglycemia. DATA SOURCES: We performed an electronic search of research databases PubMed, Scopus, CINAHL, and PsycINFO (1985-2019). STUDY SELECTION: We included randomized controlled trials of DSME interventions among U.S. adults with type 2 diabetes from racial and ethnic minority populations. DATA EXTRACTION: We extracted study parameters on DSME interventions and changes in percent hemoglobin A1c (HbA1c). DATA SYNTHESIS: A total of 106 randomized controlled trials were included. Twenty-five percent (n = 27) of interventions were exclusively individual-behavioral, 51% (n = 54) were multilevel, 66% (n = 70) were multidomain, and 42% (n = 45) were both multilevel and multidomain. Individual-behavioral interventions reduced HbA1c by -0.34 percentage points (95% CI -0.46, -0.22; I2 = 33%) (-3.7 [-5.0, -2.4] mmol/mol). Multilevel interventions reduced HbA1c by -0.40 percentage points (95% CI -0.51, -0.29; I2 = 68%) (-4.4 [-5.6, -3.2] mmol/mol). Multidomain interventions reduced HbA1c by -0.39 percentage points (95% CI -0.49, -0.29; I2 = 68%) (-4.3 [-5.4, -3.2] mmol/mol). Interventions that were both multilevel and multidomain reduced HbA1c by -0.43 percentage points (95% CI -0.55, -0.31; I2 = 69%) (-4.7 [-6.0, -3.4] mmol/mol). LIMITATIONS: The analyses were restricted to RCTs.

conclusionsMultilevel and multidomain DSME interventions had a modest impact on HbA1c. Few DSME trials have targeted the community and society levels or physical environment domain. Future research is needed to evaluate the effects of these interventions on outcomes beyond HbA1c.

Indexed as

Diabetes Mellitus, Type 2Glycemic ControlEthnic and Racial MinoritiesGlycated HemoglobinHumansSelf-ManagementUnited StatesGlycated Hemoglobin

Identifiers

PMID39190927
PMCPMC11362130

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.