Evidence map›Paper›PMID 39190743›Full record

ArticlePloS one2024

Robot-assisted gait training in patients with various neurological diseases: A mixed methods feasibility study.

Isabella Hotz, Sarah Mildner, Michaela Stampfer-Kountchev, Bianca Slamik, Christoph Blättner, Elisabeth Türtscher, Franziska Kübler, Clemens Höfer, Johanna Panzl, Michael Rücker and 2 more

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Effects of Robot-Assisted Gait Therapy on Urodynamic Changes in the Subacute Phase After Spinal Cord Injury: A Prospective Study.Medical science monitor : international medical journal of experimental and clinical research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Isabella HotzDepartment of Rehabilitation Science, Clinic for Rehabilitation Münster, Münster, Austria.
Sarah MildnerDepartment of Rehabilitation Science, Clinic for Rehabilitation Münster, Münster, Austria.
Michaela Stampfer-KountchevDepartment of Neurology, Clinic for Rehabilitation Münster, Münster, Austria.
Bianca SlamikDepartment of Neurology, Clinic for Rehabilitation Münster, Münster, Austria.
Christoph BlättnerDepartment of Neurology, Clinic for Rehabilitation Münster, Münster, Austria.
Elisabeth TürtscherDepartment of Neurology, Clinic for Rehabilitation Münster, Münster, Austria.
Franziska KüblerDepartment of Rehabilitation Science, Clinic for Rehabilitation Münster, Münster, Austria.
Clemens HöferDepartment of Neurology, Clinic for Rehabilitation Münster, Münster, Austria.
Johanna PanzlDepartment of Neurology, Clinic for Rehabilitation Münster, Münster, Austria.
Michael RückerDepartment of Neurology, Clinic for Rehabilitation Münster, Münster, Austria.
Christian BrenneisDepartment of Neurology, Clinic for Rehabilitation Münster, Münster, Austria.
Barbara SeebacherDepartment of Rehabilitation Science, Clinic for Rehabilitation Münster, Münster, Austria.ORCID 0000-0001-5699-9077

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWalking impairment represents a relevant symptom in patients with neurological diseases often compromising social participation. Currently, mixed methods studies on robot-assisted gait training (RAGT) in patients with rare neurological diseases are lacking. This study aimed to explore the feasibility, acceptability, goal attainment and preliminary effects of RAGT in patients with common and rare neurological diseases and understand the intervention context and process.

methodsA mixed-methods feasibility study was conducted at an Austrian rehabilitation centre. Twenty-eight inpatients after stroke in the subacute and chronic phases, with multiple sclerosis, Parkinson's disease, spinal cord injury, spinocerebellar ataxia, acute/chronic inflammatory demyelinating polyneuropathy and motor neuron disease were included. Patients received RAGT for 45 minutes, 4x/week, for 4 weeks. Baseline and post-intervention assessments included gait parameters, walking and balance, and questionnaires. Semi-structured observations were conducted twice during the intervention period and analysed using thematic analysis. Descriptive statistics within the respective disease groups and calculation of effect sizes for the total sample were performed. Triangulation was employed to develop a deeper understanding of the research topic.

resultsData from 26 patients (mean age 61.6 years [standard deviation 13.2]) were analysed. RAGT was highly accepted by patients and feasible, indicated by recruitment, retention, and adherence rates of 84.8% (95% confidence interval, CI 0.7-0.9), 92.2% (95% CI 0.7-1.0) and 94.0% (95% CI 91.4-96.2), respectively. Goal attainment was high, and only mild adverse events occurred. Improvements in walking speed (10-Metre Walk Test, effect size r = 0.876), walking distance (6-Minute Walk Test, r = 0.877), functional mobility (Timed Up and Go, r = 0.875), gait distance (r = 0.829) and number of steps (r = 0.834) were observed. Four themes were identified: familiarising with RAGT; enjoyment and acceptance through a trusting therapeutic relationship; actively interacting; and minimising dissatisfaction. DISCUSSION: Sufficiently powered randomised controlled trials are needed to validate our results.

trial registrationGerman Clinical Trials Register, DRKS00027887.

Indexed as

Feasibility StudiesGaitRoboticsAdultAgedExercise TherapyFemaleGait Disorders, NeurologicHumansMaleMiddle AgedNervous System DiseasesWalking

Identifiers

PMID39190743
PMCPMC11349200

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.