Evidence map›Paper›PMID 39190572›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

The SINA1-BSD1 Module Regulates Vegetative Growth Involving Gibberellin Biosynthesis in Tomato.

Yulin Yuan, Youhong Fan, Li Huang, Han Lu, Bowen Tan, Chloe Ramirez, Chao Xia, Xiangli Niu, Sixue Chen, Mingjun Gao and 3 more

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In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yulin YuanDepartment of Plant Sciences, University of Idaho, Moscow, ID, 83844, USA.
Youhong FanDepartment of Plant Sciences, University of Idaho, Moscow, ID, 83844, USA.
Li HuangDepartment of Plant Sciences, University of Idaho, Moscow, ID, 83844, USA.
Han LuMinistry of Education Key Laboratory for Biodiversity Science and Ecological Engineering, National Observations and Research Station for Wetland Ecosystems of the Yangtze Estuary, Institute of Biodiversity Science and Institute of Eco‑Chongming, School of Life Sciences, Fudan University, Shanghai, 200433, China.
Bowen TanDepartment of Biology, University of Mississippi, Oxford, MS, 38677, USA.
Chloe RamirezDepartment of Plant Sciences, University of Idaho, Moscow, ID, 83844, USA.
Chao XiaMaize Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Xiangli NiuSchool of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui, 230009, China.
Sixue ChenDepartment of Biology, University of Mississippi, Oxford, MS, 38677, USA.
Mingjun GaoMinistry of Education Key Laboratory for Biodiversity Science and Ecological Engineering, National Observations and Research Station for Wetland Ecosystems of the Yangtze Estuary, Institute of Biodiversity Science and Institute of Eco‑Chongming, School of Life Sciences, Fudan University, Shanghai, 200433, China.
Cankui ZhangDepartment of Agronomy, Purdue Center for Plant Biology, Purdue University, 915 Mitch Daniels Blvd, West Lafayette, IN, 47907, USA.
Yongsheng LiuSchool of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui, 230009, China.
Fangming XiaoDepartment of Plant Sciences, University of Idaho, Moscow, ID, 83844, USA.ORCID 0000-0001-6044-9465

Funding

National Institute of Food and Agriculture 2022-67014-37036National Natural Science Foundation of China 31972474
6 · The paper itself

Abstract

In plants, vegetative growth is controlled by synergistic and/or antagonistic effects of many regulatory factors. Here, the authors demonstrate that the ubiquitin ligase seven in absentia1 (SINA1) mammalian BTF2-like transcription factors, Drosophila synapse-associated proteins, and yeast DOS2-like proteins (BSD1) function as a regulatory module to control vegetative growth in tomato via regulation of the production of plant growth hormone gibberellin (GA). SINA1 negatively regulates the protein level of BSD1 through ubiquitin-proteasome-mediated degradation, and the transgenic tomato over-expressing SINA1 (SINA1-OX) resembles the dwarfism phenotype of the BSD1-knockout (BSD1-KO) tomato plant. BSD1 directly activates expression of the BSD1-regulated gene 1 (BRG1) via binding to a novel core BBS (standing for BSD1 binding site) binding motif in the BRG1 promoter. Knockout of BRG1 (BRG1-KO) in tomato also results in a dwarfism phenotype, suggesting BRG1 plays a positive role in vegetative growth as BSD1 does. Significantly, GA contents are attenuated in transgenic SINA1-OX, BSD1-KO, and BRG1-KO plants exhibiting dwarfism phenotype and exogenous application of bioactive GA

Indexed as

Gene Expression Regulation, PlantGibberellinsSolanum lycopersicumPhenotypePlant Growth RegulatorsPlant ProteinsPlants, Genetically ModifiedTranscription FactorsGibberellinsPlant Growth RegulatorsPlant ProteinsTranscription FactorsBRG1BSD1gibberellinSINA1tomatotranscription factorubiquitin ligase

Identifiers

PMID39190572
PMCPMC11633369

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.