Evidence map›Paper›PMID 39190473›Full record

ArticleFuture medicinal chemistry2024

Design, semi-synthesis and bioevaluation of koumine-like derivatives as potential antitumor agents

Xingjun Xu, Yan Yu, Zhiwei Wang, Han Zhou, Ling Zhang, Hao Wang, Dian Liu, Yanfang Liu, Jixia Wang, Yaopeng Zhao and 1 more

Abstract read
In one paragraph

Article in Future medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xingjun XuKey Laboratory of Phytochemistry and Natural Medicines, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116034,China.
Yan YuKey Laboratory of Phytochemistry and Natural Medicines, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116034,China.
Zhiwei WangKey Laboratory of Phytochemistry and Natural Medicines, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116034,China.
Han ZhouKey Laboratory of Phytochemistry and Natural Medicines, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116034,China.
Ling ZhangGanjiang Chinese Medicine Innovation Center, Nanchang, 330000, China.
Hao WangGanjiang Chinese Medicine Innovation Center, Nanchang, 330000, China.
Dian LiuKey Laboratory of Phytochemistry and Natural Medicines, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116034,China.
Yanfang LiuKey Laboratory of Phytochemistry and Natural Medicines, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116034,China.
Jixia WangKey Laboratory of Phytochemistry and Natural Medicines, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116034,China.
Yaopeng ZhaoKey Laboratory of Phytochemistry and Natural Medicines, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116034,China.
Xinmiao LiangKey Laboratory of Phytochemistry and Natural Medicines, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116034,China.

Funding

Natural Science Foundation of Jiangxi Province 20224BAB216003Science and Technology Plan of Liaoning Province (2023-MS-013)
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsApoptosisCell ProliferationDrug DesignDrug Screening Assays, AntitumorAnimalsCell Line, TumorDioxolanesHumansIndole AlkaloidsMiceMolecular StructureNF-kappa BReactive Oxygen SpeciesStructure-Activity RelationshipAntineoplastic AgentsDioxolanesIndole AlkaloidskoumineNF-kappa BReactive Oxygen SpeciesantitumorKouminestructural modificationstructure and activity relationship

Identifiers

PMID39190473
PMCPMC11352711

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.