Evidence map›Paper›PMID 39190358›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Direct evidence for a deprotonated lysine serving as a H-bond "acceptor" in a photoreceptor protein.

Takayuki Nagae, Mitsuhiro Takeda, Tomoyasu Noji, Keisuke Saito, Hiroshi Aoyama, Yohei Miyanoiri, Yutaka Ito, Masatsune Kainosho, Yuu Hirose, Hiroshi Ishikita and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Genomic analysis highlights a novel class of DPCF-type cyanobacteriochrome.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Takayuki NagaeDepartment of Molecular Biophysics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan.ORCID 0000-0001-7016-5183
Mitsuhiro TakedaDepartment of Molecular Biophysics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan.
Tomoyasu NojiResearch Center for Advanced Science and Technology, The University of Tokyo, Meguro-ku, Tokyo 153-8904, Japan.ORCID 0000-0001-9468-2038
Keisuke SaitoResearch Center for Advanced Science and Technology, The University of Tokyo, Meguro-ku, Tokyo 153-8904, Japan.ORCID 0000-0002-2293-9743
Hiroshi AoyamaDepartment of Molecular Biophysics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan.
Yohei MiyanoiriResearch Center for State-of-the-Art Functional Protein Analysis, Institute for Protein Research, Osaka University, Suita, Osaka 565-0871, Japan.ORCID 0000-0001-6889-5160
Yutaka ItoDepartment of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Hachioji 192-0397, Japan.ORCID 0000-0002-1030-4660
Masatsune KainoshoDepartment of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Hachioji 192-0397, Japan.ORCID 0000-0002-5229-7251
Yuu HiroseDepartment of Applied Chemistry and Life Science, Toyohashi University of Technology, Toyohashi, Aichi 441-8580, Japan.ORCID 0000-0003-1116-8979
Hiroshi IshikitaResearch Center for Advanced Science and Technology, The University of Tokyo, Meguro-ku, Tokyo 153-8904, Japan.ORCID 0000-0002-5849-8150
Masaki MishimaDepartment of Molecular Biophysics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan.ORCID 0000-0001-7626-7287

Funding

JSPS KAKENHI JP20H03217JSPS KAKENHI JP22H02562JSPS KAKENHI JP23H02444JSPS KAKENHI JP23H04963JSPS KAKENHI JP24H02094JSPS KAKENHI JP24K01986
6 · The paper itself

Abstract

Deprotonation or suppression of the p

Indexed as

Hydrogen BondingLysineMagnetic Resonance SpectroscopyModels, MolecularProtonsLysineProtonscyanobacteriochromeH-bondlysineNMRtrans-H-bond J coupling

Identifiers

PMID39190358
PMCPMC11388336

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.