Evidence map›Paper›PMID 39190345›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

The deubiquitinase Usp7 in

Cathleen M Lake, Jennifer Gardner, Salam Briggs, Zulin Yu, Grace McKown, R Scott Hawley

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Active maintenance of meiosis-specific chromosome structures inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Active maintenance of meiosis-specific chromosome structures inbioRxiv : the preprint server for biology · 2025
    Article
  4. Make it or break it: Protein homeostasis in the synaptonemal complex.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Cathleen M LakeStowers Institute for Medical Research, Kansas City, MO 64110.
Jennifer GardnerStowers Institute for Medical Research, Kansas City, MO 64110.
Salam BriggsStowers Institute for Medical Research, Kansas City, MO 64110.
Zulin YuStowers Institute for Medical Research, Kansas City, MO 64110.
Grace McKownStowers Institute for Medical Research, Kansas City, MO 64110.
R Scott HawleyStowers Institute for Medical Research, Kansas City, MO 64110.

Funding

Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
NIGMS NIH HHS R01 GM084947Stowers Institute for Medical Research (SIMR) Hawley Lab
6 · The paper itself

Abstract

Meiosis is a form of cell division that is essential to sexually reproducing organisms and is therefore highly regulated. Each event of meiosis must occur at the correct developmental stage to ensure that chromosomes are segregated properly during both meiotic divisions. One unique meiosis-specific structure that is tightly regulated in terms of timing of assembly and disassembly is the synaptonemal complex (SC). While the mechanism(s) for assembly and disassembly of the SC are poorly understood in

Indexed as

Drosophila melanogasterDrosophila ProteinsSynaptonemal ComplexAnimalsCrossing Over, GeneticMaleMeiosisUbiquitin-Specific Peptidase 7Drosophila ProteinsUbiquitin-Specific Peptidase 7deubiquitinaseDUBmeiosisSCUsp7

Identifiers

PMID39190345
PMCPMC11388383

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.