Evidence map›Paper›PMID 39189854›Full record

ArticleAmerican journal of respiratory and critical care medicine2024

Elexacaftor/Tezacaftor/Ivacaftor Markedly Reduces

Sarah J Morgan, David P Nichols, Windy Ni, Gina Hong, Stephen J Salipante, George M Solomon, Steven M Rowe, John P Clancy, Robert A Cramer, Pradeep K Singh

Abstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Home sputum collection forERJ open research · 2025
    Article
  4. Article
  5. Review
  6. Deleterious effect ofERJ open research · 2025
    Article
  7. Review
  8. Recent developments inMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sarah J MorganDepartments of Microbiology and Medicine, University of Washington, Seattle, Washington, USA.
David P NicholsCystic Fibrosis Foundation, Bethesda, Maryland, USA.ORCID 0000-0001-8611-7960
Windy NiDepartments of Microbiology and Medicine, University of Washington, Seattle, Washington, USA.
Gina HongDepartment of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-9321-8399
Stephen J SalipanteDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA.ORCID 0000-0001-8355-6992
George M SolomonDepartment of Medicine, University of Alabama, Birmingham, Alabama, USA; and.ORCID 0000-0002-2969-5518
Steven M RoweCystic Fibrosis Foundation, Bethesda, Maryland, USA.ORCID 0000-0001-9045-0133
John P ClancyDepartment of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Robert A CramerDepartment of Microbiology and Immunology, Dartmouth Geisel School of Medicine , Hanover, New Hampshire, USA.
Pradeep K SinghDepartments of Microbiology and Medicine, University of Washington, Seattle, Washington, USA.

Funding

Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI Christopher Hooper Goss, Lucas R Hoffman · 2010 to 2026
$21.4M
Translational Research CoreP30DK117469 · NIDDK · DARTMOUTH COLLEGE · PI DEAN R MADDEN · 2018 to 2026
$13.9M
Field Study to Understand Progression of Chronic Airway InfectionR01HL148274 · NHLBI · UNIVERSITY OF WASHINGTON · PI EMOND, MARY J, SINGH, PRADEEP K · 2019 to 2022
$2.9M
3D Ultrasound Guidance of Interventional DevicesR01HL089507 · NHLBI · DUKE UNIVERSITY · PI SMITH, STEPHEN WILLIAM · 2008 to 2012
$2.8M
Cystic Fibrosis Foundation SINGH19R0Cystic Fibrosis Foundation STANTO19R0NHLBI NIH HHS DK089507NHLBI NIH HHS DK117469NHLBI NIH HHS R01 HL148274NHLBI NIH HHS R01HL148274NIDDK NIH HHS P30 DK089507NIDDK NIH HHS P30 DK117469
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39189854
PMCPMC12042367

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.